tag:blogger.com,1999:blog-39656717268301280982024-03-05T05:17:37.537-05:00dementia views you can useSusan Berg, dementia expert, shares practical help for caregivers of those with dementia including easy to do activitiesexperienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.comBlogger1439125tag:blogger.com,1999:blog-3965671726830128098.post-63798435306485980532019-09-26T13:22:00.000-04:002019-09-26T13:22:00.998-04:00"Nanoparticles" of silver in common products could lead to Alzheimer"s<span style="font-size: large;"><a href="http://www.sdu.dk/en/" rel="nofollow" style="background-color: white; color: #33aaff; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: small; font-style: italic;" target="_blank"><strong>University of Southern Denmark</strong></a></span><br />
<span style="font-size: large;"><img alt="Image result for small particle picture" src="data:image/jpeg;base64,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" /></span><br />
<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Alzheimer's is characterized by an overproduction of free radicals in cells. That's why incredibly tiny "nanoparticles" of silver, found in supplements, cosmetics and food packaging, worry scientists. Hear their concerns, as well as products to avoid.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;"></a></span><br />
<hr style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" />
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Nanoparticles of silver, found in e.g. dietary supplements, cosmetics and food packaging, are worrying scientists. A trailblazing study from the University of Southern Denmark shows that nano-silver can penetrate our cells and cause damage.</span></span><br />
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 28px; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
Antibacterial Benefits</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Silver has an antibacterial effect and therefore the food and cosmetic industry often coat their products with silver nanoparticles. Nano-silver can be found in:</span></span><br />
<ol style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">
<li style="margin: 0px 0px 0.25em; padding: 0px;">Drinking bottles</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Cosmetics</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Band aids</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Toothbrushes</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Running socks</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Refrigerators</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Washing machines</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Food packagings.</li>
</ol>
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 28px; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
Cellular Changes</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">"Silver as a metal does not pose any danger, but when you break it down to nano-sizes, the particles become small enough to penetrate a cell wall. If nano-silver enters a human cell, it can cause changes in the cell," explain Associate Professor Frank Kjeldsen and PhD Thiago Verano-Braga, Department of Biochemistry and Molecular Biology at the University of Southern Denmark.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Together with their research colleagues they have just published the results of a study of such cell damages in the journal </span><em style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">ACS Nano</em><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">The researchers examined human intestinal cells, as they consider these to be most likely to come into contact with nano-silver, ingested with food.</span></span><br />
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 28px; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
Free Radicals in Cells</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">"We can confirm that nano-silver leads to the formation of harmful, so called free radicals in cells. We can also see that there are changes in the form and amount of proteins. This worries us," say Frank Kjeldsen and Thiago Verano-Braga.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">A large number of serious diseases are characterized by the fact that there is an overproduction of free radicals in cells. This applies to cancer and neurological diseases such as Alzheimer's and Parkinson's.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Kjeldsen and Verano-Braga emphasizes that their research is conducted on human cells in a laboratory, not based on living people. They also point out that they do not know how large a dose of nano-silver, a person must be exposed to for the emergence of cellular changes.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">"We don't know how much is needed, so we cannot conclude that nano-silver can make you sick. But we can say that we must be very cautious and worried when we see an overproduction of free radicals in human cells," they say.</span></span><br />
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Dietary Supplement</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Nano-silver is also sold as a dietary supplement, promising to have an antibacterial, anti-flu and cancer-inhibatory effect. The nano-silver should also help against low blood counts and bad skin. In the EU, the marketing of dietary supplements and foods with claims to have medical effects is not allowed. But the nano-silver is easy to find and buy online.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">In the wake of the Uiversity of Southern Denmark-research, the </span><b style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Danish Veterinary and Food Administration now warns against taking dietary supplements with nano-silver</b><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">"The recent research strongly suggests that it can be dangerous," says Søren Langkilde from the Danish Veterinary and Food Administration to the Danish Broadcasting Corporation (DR).</span></span><br />
<span style="font-size: large;"><a href="http://www.sdu.dk/en/" rel="nofollow" style="background-color: white; color: #33aaff; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: small; font-style: italic;" target="_blank"><strong>University of Southern Denmark</strong></a></span><br />
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<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-41246999784602067542019-09-22T14:54:00.000-04:002019-09-22T14:54:04.102-04:00Better drugs for Alzheimer's<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
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<span style="font-size: large;">nepezil (Aricept)</span></h3>
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<a href="http://www.alzheimersweekly.com/2016/07/quadrupling-donepezil.html" imageanchor="1" style="clear: left; color: #9900ff; float: left; margin-bottom: 1em; margin-right: 1em; text-decoration-line: none;"><span style="font-size: large;"><img border="0" height="150" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhrrTyJRnmpK7XuadKMr9cFHOuuXw5dpYkoJaRSmqag6cQCWhsJ-sdbcnfcVRKuorUITIx708YBBdkxou1Q7FFrGOlVzY_TGDF2sVu6f3Bs5JXmNG3QO1zLMPScJpswETiEqD5sWvM8ZGIq/s200/160729-donepezil.jpg" style="border: none; position: relative;" width="200" /></span></a></div>
<span style="font-size: large;">MEDICATION: THE WORLD'S MOST POPULAR DEMENTIA-DRUG IS DONEPEZIL. Donepezil <i>(Brand-name: <b>Aricept®</b>)</i> boosts memory & thinking in Alzheimer's. More donepezil means more boost - along with intensified side-effects. Learn how it can be safely boosted when combined with solifenacin.<br /><br /><a href="https://www.blogger.com/null" name="more"></a></span><hr />
<span style="font-size: large;"><br />IRVINE, California -- Donepezil helps Alzheimer's and other types of dementia. Doctors often minimize its use because it can have a variety of side-effects. Progressive research shows that by adding solifenacin to each pill of donepezil, a patient could potentially boost the dosage by as much as 400% without added side-effects.</span><h3 style="color: #004e00; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">How It Works</span></h3>
<span style="font-size: large;">Here's a simplified explanation of how it works.</span><div style="background: rgb(255, 255, 204); border: 2px solid rgb(255, 102, 0); float: right; margin: 10px 0px 10px 10px; padding: 8px; width: 300px;">
<table border="1" cellpadding="4" cellspacing="1" style="float: right; margin: 10px 0px 10px 10px; width: 300px;"><tbody>
<tr style="background-attachment: initial; background-clip: initial; background-image: initial; background-origin: initial; background-position: initial; background-repeat: initial; background-size: initial; color: #004e00; font-style: italic; text-align: center;"><td colspan="2" style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Early-to-Midstage Alzheimer's</span></td></tr>
<tr><th scope="col" width="137"><span style="font-size: large;">Brand Name</span></th><th scope="col" width="138"><span style="font-size: large;">Generic Name</span></th></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Aricept®</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">donepezil</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Exelon®</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">rivastigmine</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Remynil or Razadyne®</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">galantamine</span></td></tr>
<tr style="background-attachment: initial; background-clip: initial; background-image: initial; background-origin: initial; background-position: initial; background-repeat: initial; background-size: initial; color: #004e00; font-style: italic; text-align: center;"><td colspan="2" style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Drugs for Moderate-to-Severe Stage</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Namenda® or Ebixa®</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">memantine</span></td></tr>
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<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Acetylecholine is used by the brain to send messages from cell to cell.</span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">If there is not enough acetylecholine in the brain, memory and thinking start to fail.</span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Alzheimer's often experiences dangerous drops in acetylcholine.</span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Donepezil helps boost the level of acetylcholine throughout the body.</span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">This can help an Alzheimer's brain get back to normal. However, it can also overload other systems in the body, causing nausea, weight-loss and other side-effects.</span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">The brain is separated from the rest of the body by the "blood-brain barrier".</span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">A pill of donepezil travels from the stomach to the entire body. It passes through the blood-brain barrier, boosting acetylcholine in the brain.</span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Solifenacin is another drug that blocks donepezil. However, it CANNOT pass through the blood-brain barrier.</span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Therefore, it seems that solifenacin cannot get to the brain and as a result, cannot block donepezil in the brain.</span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">At the same time, solifenacin can block donepezil everywhere else in the body, stopping side-effects like nausea in the stomach.</span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">The result is no nausea or other side-effects in the body. The patient just gets the good effect in the brain.</span></li>
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<span style="font-size: large;">New Combination</span></h3>
<span style="font-size: large;">For now, researchers call this combination of donepezil-plus-solifenacin by the name CPC-201. The new combination will mean that the brain can get the benefits of a lot more donepezil with fewer side-effects.</span></div>
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<span style="font-size: large;">Chase Pharmaceuticals Corporation (Chase) announced its results from a Phase 2 study of CPC-201.</span><h3 style="color: #004e00; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">400%</span></h3>
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<a href="http://www.alzheimersweekly.com/2013/04/what-do-aricept-exelon-razadyne-do.html" style="color: #9900ff; text-decoration-line: none;"><span style="font-size: large;">What Do Aricept, Exelon & Razadyne Do?</span></a></h3>
<span style="font-size: large;"><a href="http://www.alzheimersweekly.com/2013/04/what-do-aricept-exelon-razadyne-do.html" style="color: #9900ff; text-decoration-line: none;">Teepa Snow</a><br /><b>MEDICATION VIDEO</b><br />See Teepa Snow talk about the top medications for Alzheimer's & dementia. In plain English, she explores what they do and how they work. Get clarity on Aricept, Exelon and Razadyne (generic donepezil, rivastigmine and galantamine).</span><center>
<span style="font-size: large;"><img src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh_u5nGtBpHpWNh5sH9xjtd3WJ49N8NJboKAJYKZh3lxepeyNABV9iCTH0aFOb1X6rYG-uzHBWwv6Ki2xRVKv6LfTdCr5ccMFMaXpc1ceD3E40EZy-re1S8xtQlxZaKzI9Wk4BiyBTx2KAy/s200/130428-teepa.jpg" /></span></center>
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<span style="font-size: large;">The CPC-201 Phase 2 results, presented by Thomas Chase, MD, chief scientific officer and co-founder of Chase, and the former Scientific Director and head of the Experimental Therapeutics Branch for the National Institute of Neurological Disorders and Stroke, confirmed that solifenacin attenuated donepezil adverse events, enabling the tolerable administration of doses of donepezil to as much as 400 percent of the current standard treatment of donepezil. Secondary endpoints provided signals of enhanced efficacy, as would be predicted from increased tolerable dosing of donepezil. The data were presented during an oral session at the 2016 Alzheimer’s Association Conference (AAIC) in Toronto, Canada (Abstract a12446).<br /><br />The primary endpoint of this Phase 2 single-blind, crossover trial was to safely increase the tolerated dose of donepezil from 10 mg/day up to as much as 40 mg/day. This trial consisted of 41 moderate (MMSE 10-20) Alzheimer’s type subjects who were being successfully treated with 10 mg/day of donepezil. The anticholinergic solifenacin was first titrated to 15 mg/day and then donepezil escalated to each subject’s maximum tolerated dose or to the protocol limit of 40 mg/day. Subjects then continued for a three-month maintenance period. All subjects were able to tolerably maintain above the currently approved doses of donepezil and 85 percent of subjects reached and tolerated the maximum allowable donepezil dose of 40 mg/day. Moreover, in the maintenance phase of the trial, subjects experienced significantly less dose-limiting side effects than those that would be predicted for 10 mg/day of donepezil.</span><h3 style="color: #004e00; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">A Real Difference</span></h3>
<span style="font-size: large;">Although this Phase 2 study was not designed nor powered to provide meaningful estimates of anti-dementia efficacy, both the ADAS-Cog and the CGI-I scales in the study yielded positive signals of enhanced efficacy.<br /><br />During the dose maintenance phase, at a median donepezil dose of 40 mg/day, total gastrointestinal adverse events were greatly attenuated and about 80 percent below those predicted from trials of previously approved doses of 10 mg/day of donepezil. As would be expected with a cholinergic blocker that does not cross the blood-brain barrier, solifenacin had no effect on cognitive function and there were no drug-related serious adverse events (SAE) or clinically significant cardiovascular or laboratory abnormalities. There were no drug related dropouts and no new AEs or evidence of solifenacin toxicity.<br /><br />“Pre-clinical studies have repeatedly shown that there is a strong dose/efficacy relationship associated with AChEIs. Further, PET scan studies in humans show that at the typical dose of 10 mg/day of donepezil, the central enzymatic inhibition is no greater than about 30 percent, substantially lower than that which would be expected from optimal dosing. Yet, historically, it has not been possible to tolerably increase the dose of donepezil to meaningfully higher levels,” said Douglas Ingram, chief executive officer of Chase. “We believe we have the means to finally unlock the true potential of optimally dosed AChEIs. Moreover, we are employing an efficient development and regulatory pathway and plan to commence a superiority trial versus the current gold-standard treatment for Alzheimer’s, 10 mg/day of donepezil. If successful in Phase 3, CPC-201 could be the new standard for the symptomatic treatment of Alzheimer's disease and benefit millions of suffering patients.”</span><h3 style="color: #004e00; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Technical Talk</span></h3>
<span style="font-size: large;">“We believe that adverse events have long limited AChEI dosing to suboptimal levels, in turn limiting the efficacy of donepezil and other AChEIs,” said Thomas Chase, M.D. “Our Phase 2 findings, together with those from our earlier Phase 1 studies, robustly support our hypothesis that the co-formulation of a peripheral anticholinergic with donepezil enables the safe and tolerable administration of multiples of the current standard of care doses of AChEI such as donepezil.”<br /><br />The mean change in ADAS-Cog over the course of the study showed improvement versus subject baseline and, adjusted for underlying disease progression using a multi-study meta-analysis, subjects showed a mean (± SEM) benefit of 2.45 points over 10 mg/day donepezil or 5.4 ± .84 points compared to predicted untreated disease progression. Combined Clinical Global Impression (CGI-I) scores from investigators and caregivers at 26 weeks averaged 3.1 ± .20 points, thus improving by .94 ± .20 points (p < .001; n = 16). The responder rate (as measured by those who either did not worsen or improved over the course of the study) was over 90 percent.</span><div class="moreinfo" style="border-top: 1px solid rgb(128, 128, 128); font-style: italic;">
<span style="font-size: large;"><br /><strong>MORE INFORMATION:<br /><br />About CPC-201</strong><br />Chase’s lead candidate, CPC-201, is a patent-protected combination of donepezil (an AChEI), one of the few pharmaceuticals proven to improve cognition in Alzheimer’s patients, and solifenacin, a peripherally acting cholinergic blocker.<br /><br /><strong>SOURCE:<br /><br />About Chase</strong><br />Chase Pharmaceuticals Corporation is a clinical-stage biopharmaceutical company focused on the development and commercialization of improved treatments for neurodegenerative disorders. Chase’s development program, if successful, will profoundly improve the symptomatic treatment of Alzheimer's disease. The company was co-founded by Thomas Chase, MD, the former Scientific Director and head of the Experimental Therapeutics Branch for the National Institute of Neurological Disorders and Stroke and Kathleen Clarence-Smith, MD, PhD, the former head of CNS development at each of Sanofi, Hoffmann-La Roche and Otsuka. Chase is led by its chief executive officer and president, Douglas Ingram, formerly the president of Allergan, Inc.<br /><br />Chase has closed over $24 million in funding to date, with approximately $22 million through a Series B financing led by New Rhein Healthcare Investors, LLC and including, among others, Edmond de Rothschild Investment Partners, Cipla Ventures and Brain Trust Accelerator Fund.<br /><br /><b>EDITED BY:</b><br />Peter Berger</span></div>
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<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-82598067450435128822019-09-19T13:11:00.000-04:002019-09-19T13:11:01.930-04:00How to stop the new Alzheimer's problem?<span style="font-size: large;"><img alt="Image result for dna picture" 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" /></span><br />
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<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
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<span style="font-size: large;"><span style="font-size: medium;"><span style="color: #9900ff; font-style: italic;">AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOG</span></span><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"> </span></span><br />
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<span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"><span style="font-size: large;">100 years ago, Dr. Alois Alzheimer's identified plaques and tangles as the hallmarks of Alzheimer's. In the search for a cure, scientists recently sharpened his discovery by revealing how tangles join end-to-end to create longer filaments. Drugs that can block this grouping may block Alzheimer's. Learn the latest.</span></span><br />
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"></a></span>
<hr style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" />
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Early in the course of Alzheimer's disease--long before future patients begin to notice symptoms--neurofibrillary tangles composed of tau protein aggregates begin to form in their brain cells. How toxic these aggregates are and how well they spread depend on their size. However, scientists studying tangle formation have not been able to explain why different sizes of cable-like tau aggregates appear in disease.</span></span><br />
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<span style="font-size: large;">Drugs to Inhibit Aggregation</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">But now, researchers at The Ohio State University have discovered that instead of adding just one protein at a time, fibrils of various lengths can join end-to-end to create one longer filament. The finding, which appears in the </span><a href="http://www.jbc.org/" style="background-color: white; color: #9900ff; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; text-decoration-line: none;">Journal of Biological Chemistry</a><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">, helps explain how fibrils can grow to hundreds of nanometers and could also help researchers understand mechanisms of an emerging group of drug candidates designed to inhibit tau aggregation.</span></span><br />
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<span style="font-size: large;">Two Proteins Bind, More Proteins Latch On</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Scientists can use mathematical models to describe biological processes such as fibril formation. A common simple model of tau aggregation includes two steps. In the first step, two tau proteins bind slowly, and, in the second step, additional tau molecules latch on quickly.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /></span><br />
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<span style="font-size: large;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhiSMH844YsIPv-SL_sSZ6PcTXpmofO6MONTTWE2lFtFV0IirptsR9FF22e_lldDvwee2FM5yxHtLW5cemJT9LLbnOce41MBhr3cRv4Cl3Rd5S3_5FHnNBirJ2cIbNTkFY8tEIy4f1i8XpN/s1600/190414-tangle.jpg" style="color: #9900ff; text-decoration-line: none;">Click to enlarge image, click again to shrink it (Source: Phys.org):<br /><img border="0" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhiSMH844YsIPv-SL_sSZ6PcTXpmofO6MONTTWE2lFtFV0IirptsR9FF22e_lldDvwee2FM5yxHtLW5cemJT9LLbnOce41MBhr3cRv4Cl3Rd5S3_5FHnNBirJ2cIbNTkFY8tEIy4f1i8XpN/s1600/190414-tangle.jpg" style="border: none; position: relative;" width="100%" /></a><br />Biophysicists have discovered a new mechanism by which aggregates of tau protein, called fibrils, can grow. Two fibrils can attach end-to-end. This figure shows a fibril composed of smaller fibrils labeled in three colors. The researcher labeled tau proteins with three different fluorescent dyes and allowed them to aggregate in separate test tubes. Then she mixed these different colored fibrils together in a fourth test tube. Images taken with a super-resolution fluorescence microscope showed long fibrils with short sections of each color, indicating that fibrils from original test tubes must have joined ends to form longer fibrils. Credit: Carol Huseby/Ohio State University</span></div>
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">First author Carol Huseby, a graduate student in the lab of Jeff Kuret, working in collaboration with Ralf Bundschuh, set out to expand this mathematical model to include other known ways that tau fibrils behave. Scientists have observed, for example, that sometimes one fibril fragments into two. Other times, a new fibril can nucleate in the middle of an existing fibril.</span></span><br />
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<span style="font-size: large;">Simple Two-Step Model</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">The simple two-step model predicted that a test tube filled with purified tau protein would result in a large number of short fibrils. But Huseby knew that when researchers look at aggregated tau protein under a microscope, they see a smaller number of long fibrils. That discrepancy suggested that something was happening in the real world that hadn't been accounted for in the model. They hypothesized that perhaps short fibrils could attach end-to-end to get longer.</span></span><br />
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<span style="font-size: large;">Huseby ran a series of experiments to test the hypothesis. In one, first she labeled tau proteins with three different fluorescent colors and allowed them to aggregate in separate test tubes. Then she mixed these different colored fibrils together in a fourth test tube.</span><h3 style="color: #004e00; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Long Fibrils, Short Sections</span></h3>
<span style="font-size: large;">Images taken with a super-resolution fluorescence microscope showed long fibrils with short sections of each color, indicating that fibrils from original test tubes must have joined ends to form longer fibrils. Control experiments established that this can't be explained by labeled molecules' preference for like labels.<br /><br />After Huseby incorporated this new mechanism into the model, it produced a much better description of what purified tau proteins were really doing as they formed aggregates. This study is the first to show that the fibrils can elongate by more than a single tau protein at a time.</span><h3 style="color: #004e00; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Tau Fibrils: Cause and Effect</span></h3>
<span style="font-size: large;">Alzheimer's researchers are still trying to discern whether tau fibrils are a cause or simply an effect of the disease. One possibility is that transmission of fibrils from one cell to another may contribute to the spread of disease in the brain. A very long fibril, according to Kuret, is unlikely to spread in this way. "But once it's broken up into little pieces, those can diffuse, facilitating their movement from cell to cell."<br /><br />This study used just one type of tau. Six isoforms of different length are known, and phosphorylation and other changes increase the protein's complexity. The researchers plan to incorporate these variables in future work, and to begin to use the model to understand how tau inhibitors change the protein aggregates' behavior.<br /></span><div class="moreinfo" style="border-top: 1px solid rgb(128, 128, 128); font-style: italic;">
<span style="font-size: large;"><br /><b>SOURCE:</b></span><ul style="line-height: 1.4; list-style: disc; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px; text-indent: 0px;"><a href="https://phys.org/partners/american-society-for-biochemistry-and-molecular-biology/" style="color: #9900ff; text-decoration: none;" target="_blank"><span style="font-size: large;">AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY</span></a></li>
</ul>
<b><span style="font-size: large;">SUPPORT:</span></b><ul style="line-height: 1.4; list-style: disc; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px; text-indent: 0px;"><span style="font-size: large;">This research was funded by the<span> </span><a href="http://nih.gov/" style="color: #9900ff; text-decoration: none;">National Institutes of Health</a>.</span></li>
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<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-14772786229912667292019-09-17T14:47:00.000-04:002019-09-17T14:47:02.782-04:00How low Vitamin D increases Alzheimer's risk<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">In the largest study of its kind, not getting enough vitamin D turned out to double the risk of developing dementia and Alzheimer’s. See why supplements may not be the answer. Find out which foods to eat.</span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;"></a></span><br />
<hr style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" />
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><em style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;">MINNEAPOLIS</em><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;"> – In the largest study of its kind, researchers suggest that in older people, not getting enough vitamin D may double the risk of developing dementia and Alzheimer’s disease. The study is published in the online issue of </span><a href="http://neurology.org/lookup/doi/10.1212/WNL.0000000000000755" style="background-color: white; color: #9900ff; font-family: arial, tahoma, helvetica, freesans, sans-serif;" target="_blank">Neurology®,</a><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;"> the medical journal of the </span><a href="http://www.aan.com/" style="background-color: white; color: #9900ff; font-family: arial, tahoma, helvetica, freesans, sans-serif;" target="_blank">American Academy of Neurology</a><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">.</span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><em style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;">Continued below video...</em></span><br />
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<iframe allowfullscreen="" frameborder="0" height="315" src="https://www.youtube-nocookie.com/embed/GSjH6XPNFao?rel=0" style="height: 352.315px; left: 0px; position: absolute; top: 0px; width: 573.011px;" width="560"></iframe></div>
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">The study looked at blood levels of vitamin D, which includes vitamin D from food, supplements and sun exposure. Dietary vitamin D is found in:</span></span><br />
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<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Fatty fish such as salmon, tuna or mackerel</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Milk</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Eggs</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Cheese</span></li>
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Twice as Strong</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">"We expected to find an association between low Vitamin D levels and the risk of dementia and Alzheimer's disease, but the results were surprising—we actually found that the association was twice as strong as we anticipated," said study author David J. Llewellyn, PhD, of the University of Exeter Medical School in the United Kingdom.</span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">For the study, 1,658 people over the age of 65 who were dementia-free had their vitamin D blood levels tested. After an average of six years, 171 participants developed dementia and 102 had Alzheimer's disease.</span></span><br />
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Vitamin D Levels and Dementia Risk</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">The study found that people with low levels of vitamin D had a 53 percent increased risk of developing dementia and those who were severely deficient had a 125 percent increased risk compared to participants with normal levels of vitamin D.</span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">People with lower levels of vitamin D were nearly 70 percent more likely to develop Alzheimer's disease and those who had severe deficiency were over 120 percent more likely to develop the disease.</span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">The results remained the same after researchers adjusted for other factors that could affect risk of dementia, such as education, smoking and alcohol consumption</span></span><br />
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;"><span style="font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Clinical trials are now needed to establish whether eating foods such as oily fish or taking vitamin D supplements can delay or even prevent the onset of Alzheimer's disease and dementia. We need to be cautious at this early stage and our latest results do not demonstrate that low vitamin D levels cause dementia. That said, our findings are very encouraging, and even if a small number of people could benefit, this would have enormous public health implications given the devastating and costly nature of dementia," said Llewellyn.</span><br style="font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /></span></span><br />
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<span style="font-size: large;"><br /><b>MORE INFORMATION:</b><br />The study was supported by the National Heart, Lung, and Blood Institute, the National Institute of Neurological Disorders and Stroke, the National Institute on Aging, the Alzheimer's Association, the Mary Kinross Charitable Trust, the James Tudor Foundation, the Halpin Trust, the Age Related Diseases and Health Trust, the Norman Family Charitable Trust and the UK National Institute for Health Research. <a href="http://www.aan.com/patients" style="color: #9900ff; text-decoration-line: none;" target="_blank">www.aan.com/patients</a>.<br /><br />The American Academy of Neurology, an association of more than 27,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, stroke, migraine, multiple sclerosis, concussion, Parkinson's disease and epilepsy.<br /><br />For more information about the American Academy of Neurology, <a href="http://www.aan.com/" style="color: #9900ff; text-decoration-line: none;" target="_self">visit http://www.aan.com </a>or find us on <a href="http://www.facebook.com/AmericanAcademyofNeurology" style="color: #9900ff; text-decoration-line: none;" target="_blank">Facebook</a>, <a href="https://twitter.com/#!/AANpublic" style="color: #9900ff; text-decoration-line: none;" target="_blank">Twitter</a>, <a href="https://plus.google.com/u/0/101103447235831293532/posts#101103447235831293532/posts" style="color: #9900ff; text-decoration-line: none;" target="_blank">Google+</a> and <a href="http://www.youtube.com/aanchannel" style="color: #9900ff; text-decoration-line: none;" target="_blank">YouTube</a></span></div>
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<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-60052682091869617842019-09-13T16:40:00.000-04:002019-09-13T16:40:00.430-04:00How emotions affect those with Alzheimer's<span style="font-size: large;"><img alt="feelings" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg9XdAqgxdJ2tmb4DhoxqoUvgKy3W6qITmaUOX7XMofkakSCamienz4qrAOKAjjEpBXWXCiXqURR0eS95JWlw0sBnGKpD2Gr_h9dSaMvOP8yke24LwReD6aOCgZjmMJclAzKXYsEHoEf2n8/s200/140928-feelings.jpg" />Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">EMOTIONAL STATES of individuals with Alzheimer's are profoundly influenced by Caregivers. Learn how.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;"></a></span><br />
<hr style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" />
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">A new University of Iowa study further supports an inescapable message: caregivers have a profound influence -- good or bad -- on the emotional state of individuals with Alzheimer's disease. Patients may not remember a recent visit by a loved one or having been neglected by staff at a nursing home, but those </span><strong style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">actions can have a lasting impact on how they feel.</strong><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;"></span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">The findings of this study are published in the journal</span><em style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">, Cognitive and Behavioral Neurology.</em><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;"></span></span><br />
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Sad and Happy Movies</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">UI researchers showed individuals with Alzheimer's disease clips of sad and happy movies. The patients experienced sustained states of sadness and happiness despite not being able to remember the movies.</span></span><br />
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Emotional Life is Alive and Well</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">"This confirms that </span><strong style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">the emotional life of an Alzheimer's patient is alive and well,</strong><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">" says lead author Edmarie Guzmán-Vélez, a doctoral student in clinical psychology, a Dean's Graduate Research Fellow, and a National Science Foundation Graduate Research Fellow.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Guzmán-Vélez conducted the study with Daniel Tranel, UI professor of neurology and psychology, and Justin Feinstein, assistant professor at the University of Tulsa and the Laureate Institute for Brain Research.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Tranel and Feinstein published a paper in 2010 that predicted the importance of attending to the emotional needs of people with Alzheimer's, which is expected to affect as many as 16 million people in the United States by 2050 and cost an estimated $1.2 trillion.</span></span><br />
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 28px; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
Treating Patients, Teaching Caregivers</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">"It's extremely important to see data that support our previous prediction," Tranel says. "Edmarie's research has immediate implications for how we treat patients and how we teach caregivers."</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Despite the considerable amount of research aimed at finding new treatments for Alzheimer's, no drug has succeeded at either preventing or substantially influencing the disease's progression. Against this foreboding backdrop, the results of this study highlight the need to develop new caregiving techniques aimed at improving the well-being and minimizing the suffering for the millions of individuals afflicted with Alzheimer's.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">For this behavioral study, Guzmán-Vélez and her colleagues invited 17 patients with Alzheimer's disease and 17 healthy comparison participants to view 20 minutes of sad and then happy movies. These movie clips triggered the expected emotion: sorrow and tears during the sad films and laughter during the happy ones.</span></span><br />
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 28px; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
Remembering Scenes Vs. Remembering Feelings</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">About five minutes after watching the movies, the researchers gave participants a memory test to see if they could recall what they had just seen. As expected, the patients with Alzheimer's disease retained significantly less information about both the sad and happy films than the healthy people. In fact, four patients were unable to recall any factual information about the films, and one patient didn't even remember watching any movies.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Before and after seeing the films, participants answered questions to gauge their feelings. Patients with Alzheimer's disease reported elevated levels of either sadness or happiness for up to 30 minutes after viewing the films despite having little or no recollection of the movies.</span></span><br />
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 28px; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
Emotions Far Outlasted Memories</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Quite strikingly, the less the patients remembered about the films, the longer their sadness lasted. While sadness tended to last a little longer than happiness, both emotions far outlasted the memory of the films.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">The fact that forgotten events can continue to exert a profound influence on a patient's emotional life highlights the need for caregivers to avoid causing negative feelings and to try to induce positive feelings.</span></span><br />
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<a href="https://www.blogger.com/blogger.g?blogID=3965671726830128098" imageanchor="1" style="clear: left; float: left; margin-bottom: 1em; margin-right: 1em;"></a>Empowering Caregivers</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">According to Guzmán-Vélez, simple things that can have a lasting emotional impact on a patient's quality of life and subjective well-being include:</span></span><br />
<ul style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 1.4; list-style-image: initial; list-style-position: initial; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">Frequent visits</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">Social interactions</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">Exercise</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">Music</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">Dance</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">Jokes</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">Serving patients their favorite foods.</li>
</ul>
<span style="font-size: large;"><strong style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">Guzmán-Vélez says, "Our findings should empower caregivers by showing them that their actions toward patients really do matter."</strong><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /></span><br />
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<br /><strong>Source:</strong><ul style="line-height: 1.4; list-style-image: initial; list-style-position: initial; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><a href="http://www.uihealthcare.com/index.html" rel="nofollow" style="color: #9900ff; text-decoration-line: none;" target="_blank"><strong>University of Iowa Health Care</strong></a></li>
</ul>
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<br /><strong>Journal Reference</strong>:<br /><ol>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Edmarie Guzmán-Vélez, Justin S. Feinstein, Daniel Tranel. <strong>Feelings Without Memory in Alzheimer Disease</strong>. <em>Cognitive And Behavioral Neurology</em>, 2014; 27 (3): 117 DOI: <a href="http://dx.doi.org/10.1097/WNN.0000000000000020" rel="nofollow" style="color: #9900ff; text-decoration-line: none;" target="_blank">10.1097/WNN.0000000000000020</a></li>
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<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-90318081229100546552019-09-11T16:31:00.000-04:002019-09-11T16:34:43.583-04:00Could sleep apnea cause Alzheimer's<a href="https://www.blogger.com/blogger.g?blogID=3965671726830128098" imageanchor="1" style="clear: right; float: right; margin-bottom: 1em; margin-left: 1em;"></a><span style="font-size: large;"></span><br />
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<span style="font-size: large;"><br /></span><span style="font-size: large;"><img alt="Breathing patterns during sleep" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjJ71Py7A-bEQPpE5FaGFMt4SfppU5QAx2BXLxBpAlqnrn64nCX9H3Vb2lgSkKh6QJdVkozdCGG2u2Tc0bCGTHmVNzNoR4pqyzF_HezNdgHj43pmqU6ASy0C49oJ4uSVDDJeOrG4HBAuJBn/s200/130526-sleep.jpg" />Caregivers, and healthcare professionals,here is some great information</span><br />
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<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
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<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
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<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
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<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14.85px;">Research has long connected sleep apnea and Alzheimer's. A key study looking at Alzheimer's and sleep-disordered breathing (SDB) is opening up new "chicken-or-egg" questions: Which comes first? Just who is causing what?</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;"></a></span><br />
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<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14.85px;">An important study looking at sleep-disordered breathing (SDB) and markers for Alzheimer's disease (AD) risk in cerebrospinal fluid (CSF) and neuroimaging adds to the growing body of research linking the two.</span></span><br />
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 28px; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
Increased SDB in Elderly?</h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14.85px;">But this latest study also poses an interesting question: Could AD in its "preclinical stages" also lead to SDB and explain the increased prevalence of SDB in the elderly?</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14.85px;">"It's really a chicken and egg story," said Ricardo S. Osorio, MD, a research assistant professor at NYU School of Medicine who led the study. "Our study did not determine the direction of the causality, and, in fact, didn't uncover a significant association between the two, until we broke out the data on lean and obese patients."</span></span><br />
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When the researchers did consider body mass, they found that lean patients (defined as having a body mass index <25 ad-vulnerable="" ad="" among="" and="" atrophy="" biomarkers="" csf="" did="" fdg-pet="" glucose="" hippocampal="" hypometabolism="" in="" increased="" mri="" non-specific="" obese="" of="" p-tau="" patients="" possess="" regions="" risk="" sdb="" several="" specific="" structural="" t-tau="" using="" with="">25), glucose hypometabolism was also found in the medial temporal lobe, but was not significant in other AD-vulnerable regions.</25><br />
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10% to 20% Have SDB</h3>
"We know that about 10 to 20 percent of middle-aged adults in the United States have SDB [defined as an apnea-hypopnea index greater than 5] and that the number jumps dramatically in those over the age of 65," said Dr. Osorio, noting that studies put the percentage of people over the age of 65 with SDB between 30 and 60 percent. "We don't know why it becomes so prevalent, but one factor may be that some of these patients are in the earliest preclinical stages of AD."<br />
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According to Dr. Osorio, the biochemical harbingers of AD are present 15 to 20 years before any of its currently recognized symptoms become apparent.<br />
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The NYU study enrolled 68 cognitively normal elderly patients (mean age 71.4±5.6, range 64-87) who underwent two nights of home monitoring for SDB and were tested for at least one diagnostic indicator of AD. The researchers looked at P-Tau, T-Tau and Aβ42 in CSF, FDG-PET (to measure glucose metabolism), Pittsburgh compound B (PiB) PET to measure amyloid load, and/or structural MRI to measure hippocampal volume. Reduced glucose metabolism in AD-vulnerable regions, decreased hippocampal volume, changes in P-Tau, T-Tau and Aβ42, and increased binding of PiB-PET are recognized as markers of risk for AD and have been reported to be abnormal in healthy subjects before the disease onset.<br />
<br />
Biomarkers for AD risk were found only among lean study participants with SDB. These patients showed a linear association between the severity of SDB and CSF levels of the biomarker P-Tau (F = 5.83, t=2.41, β=0.47; p< 0.05) and between SDB and glucose hypometabolism using FDG-PET, in the medial temporal lobe (F=6.34, t=-2.52, β=-0.57,p<0 .05="" a="" ad-vulnerable="" all="" also="" amyloid="" and="" as="" burden="" but="" cingulate="" compared="" composite="" controls="" cortex="" csf="" decreased="" differences="" found="" h3="" hippocampi="" in="" lean="" measures="" no="" of="" or="" p="" patients="" pib="" positive="" posterior="" precuneus="" regions="" scans.="" score="" sdb="" showed="" smaller="" style="color: #004e00; font-size: 28px; margin: 10px 0px 5px; padding-top: 5px; position: relative;" such="" t="-2.11," the="" to="" were="" when="">2-Year Study</0></div>
Dr. Osorio and his colleagues are planning to test their hypothesis that very early stage preclinical AD brain injury that associates with these biomarkers can lead to SDB. They have proposed a two-year longitudinal study that would enroll 200 cognitively normal subjects, include AD biomarkers and treat those patients with moderate to severe SDB with continuous positive airway pressure, or CPAP, over time.<br />
<h3 style="color: #004e00; font-size: 28px; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
"Sleep Apnea Skyrockets in the Elderly"</h3>
The purpose of the new study would be to determine the "direction" of causality between SDB and preclinical AD in elderly patients. After an initial assessment, the patients would be given CPAP to treat their sleep apnea. After six months, they would be evaluated again for biomarker evidence of AD.<br />
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"If the biomarkers change, it may indicate that SDB is causing AD," explained Dr. Osorio. "If they don't change, the probable conclusion is that these patients are going to develop AD with or without CPAP, and that AD may either be causing the apneas or may simply coexist with SDB as part of aging."<br />
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Either way, Dr. Osorio believes the relationship between SDB and AD deserves further study. "Sleep apnea skyrockets in the elderly, and this fact hasn't been given the attention it deserves by the sleep world or the Alzheimer's world," Dr. Osorio said. "Sleep particularly suffers from an outmoded perception that it is an inactive physiological process, when, in reality, it is a very active part of the day for the brain."<br />
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MORE INFORMATION:<br />
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Abstract 38456<br />
<a href="http://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2013.187.1_MeetingAbstracts.A2320" style="color: #9900ff; text-decoration: none;" target="_blank">Sleep-Disordered Breathing, Aging And Risk For Alzheimer's Disease In Cognitively Normal Subjects</a><br />
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SOURCE:<br />
<a href="http://www.thoracic.org/index.php" style="color: #9900ff; text-decoration: none;" target="_blank">American Thoracic Society</a></div>
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<br />experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-68401946352921975642019-08-31T17:34:00.000-04:002019-08-31T17:34:01.763-04:00Top recipe for those with dementia<span style="font-size: large;"><img alt="Image result for quiche recipe picture" 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" /></span><br />
<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>
<span style="font-size: large;"><b style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;">Enjoy</b><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;"> a healthy brain-boost, along with great flavor, in a chicken-and-broccoli dish. This Mediterranean-style plate is loaded with neuroprotective turmeric & cumin, as well as ginger. Enhanced with brain-nutritious, delicious coconut or olive oil, the flavor is close-to-home, yet exotic at the same time!</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;"></a></span><br />
<hr style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;" />
<div style="background: rgb(255, 255, 204); border: 2px solid rgb(255, 102, 0); clear: both; color: #333333; float: right; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px; margin: 10px 0px 10px 10px; padding: 8px; width: 300px;">
For information on the health benefits of these ingredients, check out:<br />
<ol>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><a href="http://www.eat2think.com/2014/02/curry-derivative-outperforms-aricept.html" style="color: #9900ff; text-decoration: none;">J147, a Derivative of Turmeric, Outperforms Aricept (Donepezil) in Memory Tests</a></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><a href="http://www.eat2think.com/search/label/Coconut%20Oil" style="color: #9900ff; text-decoration: none;">Coconut Oil & Dementia Videos & Articles</a></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><a href="http://www.alzheimersweekly.com/2016/10/olive-oil-lettuce-protect-brain-from.html" style="color: #9900ff; text-decoration: none;">Olive Oil & Lettuce Protect Brain from Vascular Dementia</a></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><a href="http://www.eat2think.com/search/label/Mediterranean%20Diet" style="color: #9900ff; text-decoration: none;">Videos & Articles on How A Mediterranean Diet Fights Dementia</a></li>
</ol>
</div>
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;" /><b style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;">Prep Time: 30 minutes</b><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;" /><b style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;">Total Time: 30 minutes</b><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;" /><b style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;">Servings: 5 Servings</b></span><br />
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 28px; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
Ingredients</h3>
<ul style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px; margin: 0.5em 0px; padding: 0px 2.5em;" type="disc">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">1 Pound Chicken breasts</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">1 Large Head Broccoli</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">1 Onion</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">5 Cloves Garlic</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">2 Inches <a href="https://www.blogger.com/null" type="amzn">Ginger</a></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">1 Heaping Tablespoon <a href="https://www.blogger.com/null" type="amzn">Turmeric</a></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">1 Teaspoon <a href="https://www.blogger.com/null" type="amzn">Cumin</a></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">1/2 Teaspoon <a href="https://www.blogger.com/null" type="amzn">Chile Powder</a>(optional)</li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">3 - 6 Tablespoons <a href="https://www.blogger.com/null" type="amzn">coconut oil</a> or <a href="https://www.blogger.com/null" type="amzn">olive oil</a></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">1 Lemon</li>
</ul>
<h2 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 20px; font-stretch: normal; margin: 20px 0px 8px; position: relative; text-transform: uppercase;">
DIRECTIONS</h2>
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<ol style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; line-height: 20.79px;">
<li style="margin: 0px 0px 0.25em; padding: 0px;">Slice the onions into strips. Slice the chicken also into strips. Cut the broccoli into bite size chunks</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Mince the garlic and ginger together into one chunky paste.</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Saute the onions in oil until softened. 5 minutes.</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Add Ginger and Garlic Paste. Cook 1 minute</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Add Spices. Cook 1 minute</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Add chicken and broccoli. Cook until the chicken is no longer pink in the center and the broccoli has reached your desired texture. Add the juice from the lemon and mix.</li>
<li style="margin: 0px 0px 0.25em; padding: 0px;">Serve over brown rice or whole wheat couscous..</li>
</ol>
experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-18825525588760705902019-08-25T17:26:00.000-04:002019-08-25T17:29:02.170-04:00How to give those with dementia choices<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>
<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong>dementia care and choices</strong></span></em></span><br />
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<div class="separator" style="clear: both; text-align: center;">
<iframe allowfullscreen="" class="YOUTUBE-iframe-video" data-thumbnail-src="https://i.ytimg.com/vi/1TuKZqcPenA/0.jpg" frameborder="0" height="266" src="https://www.youtube.com/embed/1TuKZqcPenA?feature=player_embedded" width="320"></iframe></div>
<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-77017394249506311732019-08-18T11:37:00.000-04:002019-08-18T11:37:05.028-04:00Honor Dementia Caregivers This Labor Day (part3)<img alt="Related image" src="https://encrypted-tbn0.gstatic.com/images?q=tbn:ANd9GcRc_npiG-gzwtT2zheTEQVK4Zi4sgZPh4cU8M7LACBf7ayXyZdx" /><br />
<span style="font-size: large;">Here is a great <a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR">dementia resource</a> for caregivers and healthcare professionals, </span><br />
<span style="font-size: large;"><br /></span>
<span style="font-size: large;">Here is information on being the best <a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6">caregiver</a> you can be</span><br />
<span style="font-size: large;"><br /></span>
<span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an <a href="http://easyceu.com/idevaffiliate/pages/50.php">easyceu</a> or two</span><br />
<span style="font-size: large;"><br /></span>
<span style="font-size: large;"><br /></span>
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiGoNleRG9j8Bu18wWVMzEQgX3bENu6OlnZbtA255FGqOI2NB2MpVNeHeOpDizD99SmUhLh_Ige2RVx0If8bH36kSzzcpYwdsla68coHVdsxGij4n1uwDt7bkpxPTuJQe9jGjwo90jWnLtR/s1600-h/img029ccjpg.jpg"><span style="font-size: large;"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5353788785636212642" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiGoNleRG9j8Bu18wWVMzEQgX3bENu6OlnZbtA255FGqOI2NB2MpVNeHeOpDizD99SmUhLh_Ige2RVx0If8bH36kSzzcpYwdsla68coHVdsxGij4n1uwDt7bkpxPTuJQe9jGjwo90jWnLtR/s400/img029ccjpg.jpg" style="cursor: hand; cursor: pointer; display: block; height: 139px; margin: 0px auto 10px; text-align: center; width: 104px;" /></span></a><br />
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<span style="font-size: large;">How Extraordinary Americans Do Extraordinary Things</span><br />
<span style="font-size: large;">The fifth reason for honoring those caring for a dementia person is all the time they devote to this job. The caregiver is most likely responsible for everything from cleaning to cooking to shopping to yard work. The list seems endless. These tasks are even more difficult because while the caregiver is doing them, he must also keep the dementia person safe.</span><br />
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<span style="font-size: large;">According to a report published by the national Alzheimer's Association, ten million caregivers provided 83 billion dollars worth of care in 2005.</span><br />
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<span style="font-size: large;">So this Labor Day while you are relaxing or celebrating the end of summer, think about those 10 million dementia caregivers and all the under appreciated hard work they do, everyday, seven days a week, sometimes 24 hours a day. If you know someone with this challenging task, call them, thank them and offer a helping hand</span><br />
<br />experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-48916836637036373662019-08-14T09:36:00.000-04:002019-08-14T09:36:02.685-04:00Honor Dementia Caregivers This Labor Day (part 2)<img alt="Related image" src="https://encrypted-tbn0.gstatic.com/images?q=tbn:ANd9GcR3GVLprSa3MavlNOBP-6w8DsyeXD0hLLS6fxkp2Xywy1Cz7mrQ" /><br />
<span style="font-size: large;">Here is a great <a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR">dementia resource</a> for caregivers and healthcare professionals, </span><br />
<span style="font-size: large;"><br /></span>
<span style="font-size: large;">Here is information on being the best <a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6">caregiver</a> you can be</span><br />
<span style="font-size: large;"><br /></span>
<span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an <a href="http://easyceu.com/idevaffiliate/pages/50.php">easyceu</a> or two</span><br />
<span style="font-size: large;"><br /></span>
<span style="font-size: large;"><br /></span>
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<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiGoNleRG9j8Bu18wWVMzEQgX3bENu6OlnZbtA255FGqOI2NB2MpVNeHeOpDizD99SmUhLh_Ige2RVx0If8bH36kSzzcpYwdsla68coHVdsxGij4n1uwDt7bkpxPTuJQe9jGjwo90jWnLtR/s1600-h/img029ccjpg.jpg"><span style="font-size: large;"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5353788785636212642" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiGoNleRG9j8Bu18wWVMzEQgX3bENu6OlnZbtA255FGqOI2NB2MpVNeHeOpDizD99SmUhLh_Ige2RVx0If8bH36kSzzcpYwdsla68coHVdsxGij4n1uwDt7bkpxPTuJQe9jGjwo90jWnLtR/s400/img029ccjpg.jpg" style="cursor: hand; cursor: pointer; display: block; height: 139px; margin: 0px auto 10px; text-align: center; width: 104px;" /></span></a><br />
<span style="font-size: large;">The second reason to pay tribute to ones caring for someone with dementia is their resourcefulness. Caregivers are good at coming up with unique strategies for managing and paying for the supervision of their loved one. They may get help from attending a support group in person or online. However, they are the ones ultimately responsible for a workable plan of care.</span><br />
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<span style="font-size: large;">Third is recognizing that many perform physically demanding aspects of a dementia persons' care. Many do the bathing, feeding and toileting of their family member with dementia. These tasks are difficult because many with dementia are confused and combative.</span><br />
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<span style="font-size: large;">Next, these caregivers should be honored for all the time they devote to all aspects of a dementia persons' life. As just mentioned, most caregivers are responsible for the physical aspects of care. But they also must engage their loved ones in meaningful activities throughout the day and sometimes well into the night. Fortunately many take advantage of adult day care to ease the burden. Unfortunately, some dementia folks refuse to participate in or have behaviors that preclude them from attending these worthwhile programs.</span><br />
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<br />experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-59636256248268944872019-08-11T07:32:00.000-04:002019-08-11T16:48:43.297-04:00Honor Dementia Caregivers This Labor Day<span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professinals, </span><br />
<span style="font-size: large;"></span><br />
<span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br />
<span style="font-size: large;"></span><br />
<span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-size: large;">easyceu</span></a><span style="font-size: large;"> or two</span><br />
<span style="font-size: large;"></span><br />
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiGoNleRG9j8Bu18wWVMzEQgX3bENu6OlnZbtA255FGqOI2NB2MpVNeHeOpDizD99SmUhLh_Ige2RVx0If8bH36kSzzcpYwdsla68coHVdsxGij4n1uwDt7bkpxPTuJQe9jGjwo90jWnLtR/s1600-h/img029ccjpg.jpg"><span style="font-size: large;"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5353788785636212642" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiGoNleRG9j8Bu18wWVMzEQgX3bENu6OlnZbtA255FGqOI2NB2MpVNeHeOpDizD99SmUhLh_Ige2RVx0If8bH36kSzzcpYwdsla68coHVdsxGij4n1uwDt7bkpxPTuJQe9jGjwo90jWnLtR/s400/img029ccjpg.jpg" style="cursor: pointer; display: block; height: 139px; margin: 0px auto 10px; text-align: center; width: 104px;" /></span></a><br />
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<span style="font-size: large;"></span><br />
<span style="font-size: large;">How Extraordinary Americans Do Extraordinary Things</span><br />
<span style="font-size: large;">According to the United States government Labor Day, celebrates the contributions workers have made to the strength, prosperity, and well-being of America. Dementia caregivers certainly meet these criteria. Because over 5 million Americans have been diagnosed with dementia, there are approximately 10 million caregivers attending to them. This is a hard job that they did not sign up for but was thrust upon them. Honor them this Labor Day for all the difficult work they do.</span><br />
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<span style="font-size: large;">The first reason to honor a caregiver is for the financial burden they incur when caring for a person with dementia. First the family has consulted an Elder law attorney to get all the finances in order. </span><br />
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<span style="font-size: large;">Most likely the caregiver had to cut back on the hours of paid employment. Despite using all the resources out there, all expenses for the care of a dementia person will not be covered. That means go without, or pay for necessary items out of pocket</span><br />
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<span style="font-size: large;">come back soon for more on this</span> experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-69327378050652295872019-08-07T11:00:00.000-04:002019-08-07T11:00:10.478-04:00How to MEND memory<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><img alt="Related image" src="https://encrypted-tbn0.gstatic.com/images?q=tbn:ANd9GcQy_gSiOdsJBgOrLmTYAzC82FgNn7UWKgPRjr0hlAqy7ZZYYzwK" /></span><br />
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<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">MEND is UCLA's 25-step personalized program to reverse memory loss. Nine of 10 participants displayed significant memory improvements. Learn how. Includes a chart summing-up the 25 steps. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"></a><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;"></span></span><br />
<hr style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" />
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">MEND is a novel, personalized and comprehensive program to reverse memory loss. In a recent MEND study, nine of 10 participants displayed subjective or objective improvement in their memories, beginning within three to six months after the program's start. </span><strong style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Of the six patients who had to discontinue working or were struggling with their jobs at the time they joined the study, all were able to return to work or continue working with improved performance.</strong><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><em style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Continued below video...</em><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;"></span></span><br />
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<iframe allowfullscreen="" frameborder="0" height="270" src="https://abc7news.com/video/embed/?pid=336963" style="height: 352.315px; left: 0px; position: absolute; top: 0px; width: 573.011px;" width="476"></iframe></div>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Improvements have been sustained, and as of this writing, the longest patient follow-up is two and one-half years from initial treatment. These first ten included patients with memory loss associated with Alzheimer's disease (AD), amnestic mild cognitive impairment (aMCI), or subjective cognitive impairment (SCI; when a patient reports cognitive problems). One patient, diagnosed with late stage Alzheimer's, did not improve.</span></span><br />
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<h3 style="color: #004e00; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">MEND: 25-Step Memory Program</span></h3>
<table style="border: 1px solid rgb(0, 0, 0);"><tbody>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><strong><u><span style="font-size: large;">Goal</span></u></strong></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><strong><u><span style="font-size: large;">Approach</span></u></strong></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><strong><u><span style="font-size: large;">Notes</span></u></strong></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Optimize diet: minimize simple carbohydrates, minimize inflammation.</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Patients given choice of several low glycemic, low inflammatory, low grain diets.</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Minimize inflammation, minimize insulin resistance.</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Enhance autophagy, ketogenesis</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Fast 12 hr each night, including 3 hr prior to bedtime.</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Reduce insulin levels, reduce Aβ.</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Reduce stress</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Personalized—yoga or meditation or music, etc.</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Reduction of cortisol, CRF, stress axis.</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Optimize sleep</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">8 hr sleep per night; melatonin 0.5mg po qhs; Trp 500mg po 3x/wk if awakening. Exclude sleep apnea.</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Exercise</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">30-60' per day, 4-6 days/wk</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Brain stimulation</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Posit or related</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Homocysteine <7 font=""></7></span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Me-B12, MTHF, P5P; TMG if necessary</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Serum B12 >500</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Me-B12</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">CRP <1 .0="" a="">1.5</1></span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Anti-inflammatory diet; curcumin; DHA/EPA; optimize hygiene</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Critical role of inflammation in AD</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Fasting insulin <7 font="" hgba1c=""></7></span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Diet as above</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Type II diabetes-AD relationship</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Hormone balance</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Optimize fT3, fT4, E2, T, progesterone, pregnenolone, cortisol</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">GI health</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Repair if needed; prebiotics and probiotics</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Avoid inflammation, autoimmunity</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Reduction of Aβ</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Curcumin, Ashwagandha</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Cognitive enhancement</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Bacopa monniera, MgT</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">25OH-D3 = 50-100ng/ml</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Vitamins D3, K2</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Increase NGF</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">H. erinaceus or ALCAR</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Provide synaptic structural components</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Citicoline, DHA</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Optimize antioxidants</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Mixed tocopherols and tocotrienols, Se, blueberries, NAC, ascorbate, α-lipoic acid</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Optimize Zn:fCu ratio</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Depends on values obtained</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Ensure nocturnal oxygenation</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Exclude or treat sleep apnea</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Optimize mitochondrial function</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">CoQ or ubiquinol, α-lipoic acid, PQQ, NAC, ALCAR, Se, Zn, resveratrol, ascorbate, thiamine</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Increase focus</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Pantothenic acid</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Acetylcholine synthesis requirement</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Increase SirT1 function</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Resveratrol</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Exclude heavy metal toxicity</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Evaluate Hg, Pb, Cd; chelate if indicated</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">CNS effects of heavy metals</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">MCT effects</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Coconut oil or Axona</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"></td></tr>
</tbody></table>
<i><span style="font-size: large;"><strong>KEY:</strong><br />Hg, mercury; Pb, lead; Cd, cadmium; MCT, medium chain triglycerides; PQQ, polyquinoline quinone; NAC, N-acetyl cysteine; CoQ, coenzyme Q; ALCAR, acetyl-L-carnitine; DHA, docosahexaenoic acid; MgT, magnesium threonate; fT3, free triiodothyronine; fT4, free thyroxine; E2, estradiol; T, testosterone; Me-B12, methylcobalamin; MTHF, methyltetrahydrofolate; P5P, pyridoxal-5-phosphate; TMG, trimethylglycine; Trp, tryptophan</span></i></div>
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Encouraging Findings</span></h3>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">The study, which comes jointly from the UCLA Mary S. Easton Center for Alzheimer's Disease Research and the Buck Institute for Research on Aging, is the first to suggest that memory loss in patients may be reversed, and improvement sustained, using a complex therapeutic program that involves comprehensive changes in diet, brain stimulation, exercise, optimization of sleep, specific pharmaceuticals and vitamins, and multiple additional steps that affect brain chemistry.</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">The findings, <a href="http://www.impactaging.com/papers/v6/n9/full/100690.html" style="color: #9900ff; text-decoration-line: none;" target="_blank">published in the current online edition of the journal <em>Aging</em></a>, "are very encouraging. However, at the current time the results are anecdotal, and therefore a more extensive, controlled clinical trial is warranted," said Dale Bredesen, the Augustus Rose Professor of Neurology and Director of the Easton Center at UCLA, a professor at the Buck Institute, and the author of the paper.</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">In the case of Alzheimer's disease, Bredesen notes, there is not one drug that has been developed that stops or even slows the disease's progression, and drugs have only had modest effects on symptoms. "In the past decade alone, hundreds of clinical trials have been conducted for Alzheimer's at an aggregate cost of over a billion dollars, without success," he said.</span></div>
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Combination Therapy</span></h3>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">Other chronic illnesses such as cardiovascular disease, cancer, and HIV, have been improved through the use of combination therapies, he noted. Yet in the case of Alzheimer's and other memory disorders, comprehensive combination therapies have not been explored. Yet over the past few decades, genetic and biochemical research has revealed an extensive network of molecular interactions involved in AD pathogenesis. "That suggested that a broader-based therapeutics approach, rather than a single drug that aims at a single target, may be feasible and potentially more effective for the treatment of cognitive decline due to Alzheimer's," said Bredesen.</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">While extensive preclinical studies from numerous laboratories have identified single pathogenetic targets for potential intervention, in human studies, such single target therapeutic approaches have not borne out. But, said Bredesen, it's possible addressing multiple targets within the network underlying Alzheimer's may be successful even when each target is affected in a relatively modest way. "In other words," he said, "the effects of the various targets may be additive, or even synergistic."</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">Given this, Bredesen thought that rather than a single targeted agent, the solution might be a systems type approach, the kind that is in line with the approach taken with other chronic illnesses -- a multiple-component system.</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">"The existing Alzheimer's drugs affect a single target, but Alzheimer's disease is more complex. Imagine having a roof with 36 holes in it, and your drug patched one hole very well -- the drug may have worked, a single "hole" may have been fixed, but you still have 35 other leaks, and so the underlying process may not be affected much."</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">“The shift to applying a broad <strong>combination therapy</strong> to Alzheimer’s is a crucial turning point towards effectively treating Alzheimer’s disease,” says Dr. Marwan N. Sabbagh, Research Professor of Neurology at the University of Arizona College of Medicine in Phoenix</span></div>
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Personalized Approach</span></h3>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">Bredesen's approach is personalized to the patient, based on extensive testing to determine what is affecting the plasticity signaling network of the brain. As one example, in the case of the patient with a demanding job who was forgetting her way home, her therapeutic program consisted of some, but not all of the components involved with Bredesen's therapeutic program, and included:</span></div>
<ul style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; line-height: 1.4; list-style-image: initial; list-style-position: initial; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(1) eliminating all simple carbohydrates, leading to a weight loss of 20 pounds;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(2) eliminating gluten and processed food from her diet, with increased vegetables, fruits, and non-farmed fish;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(3) to reduce stress, she began yoga;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(4) as a second measure to reduce the stress of her job, she began to meditate for 20 minutes twice per day;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(5) she took melatonin each night;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(6) she increased her sleep from 4-5 hours per night to 7-8 hours per night;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(7) she took methylcobalamin each day;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(8) she took vitamin D3 each day;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(9) fish oil each day;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(10) CoQ10 each day;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(11) she optimized her oral hygiene using an electric flosser and electric toothbrush;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(12) following discussion with her primary care provider, she reinstated hormone replacement therapy that had been discontinued;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(13) she fasted for a minimum of 12 hours between dinner and breakfast, and for a minimum of three hours between dinner and bedtime;</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">(14) she exercised for a minimum of 30 minutes, 4-6 days per week.</span></li>
</ul>
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Pluses & Minuses</span></h3>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">The results for nine of the 10 patients reported in the paper suggest that memory loss may be reversed, and improvement sustained with this therapeutic program, said Bredesen. "This is the first successful demonstration," he noted, but he cautioned that the results are anecdotal, and therefore a more extensive, controlled clinical trial is needed. "The current, anecdotal results require a larger trial, not only to confirm or refute the results reported here, but also to address key questions raised, such as the degree of improvement that can be achieved routinely, how late in the course of cognitive decline reversal can be effected, whether such an approach may be effective in patients with familial Alzheimer's disease, and last, how long improvement can be sustained," he said.</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">The downside to this program is its complexity. It is not easy to follow, with the burden falling on the patients and caregivers, and none of the patients were able to stick to the entire protocol.</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">On the other hand, the fact that there was such great memory improvement in so many patients shows that <strong>this is not an all-or-nothing program.</strong> Even doing some of the program's steps was enough to improve memory.</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">Even better, said Bredesen, are the program's side effects: "It is noteworthy that the major side effect of this therapeutic system is <strong>improved health and an optimal body mass index</strong>, a stark contrast to the side effects of many drugs."</span></div>
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Big Trial, Rapid Results</span></h3>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;"><a href="http://www.alzheimersweekly.com/2014/10/www.museslabs.com" style="color: #9900ff; text-decoration-line: none;" target="_blank">Muses Labs</a> will soon launch a two-year observational study to conduct a large-scale trial of the MEND program. The trial will include 200+ participants with Alzheimer's disease, at selected medical facilities across the country.</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">Says Muses Labs’ CEO Vik Chandra, “Muses Labs intends to utilize the Internet and recent technology innovations to make personalized combination therapy practical and accessible to every individual with Alzheimer’s disease around the world.”</span></div>
<div style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<span style="font-size: large;">As the therapy does not rely upon new drugs, but rather an innovative combination of existing pharma and broader-based therapeutics, wider availability is only a couple of years away.</span></div>
<span style="font-size: large;"></span><br />
<div class="moreinfo" style="background-color: white; border-top: 1px solid rgb(128, 128, 128); color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic;">
<strong><span style="font-size: large;">Sources:</span></strong><br />
<ul style="line-height: 1.4; list-style-image: initial; list-style-position: initial; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><a href="http://www.ucla.edu/health-system/" rel="nofollow" style="color: #9900ff; text-decoration-line: none;" target="_blank"><span style="font-size: large;">University of California, Los Angeles (UCLA), Health Sciences</span></a></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Muses Labs at <a href="http://www.alzheimersweekly.com/2014/10/www.museslabs.com" rel="nofollow" style="color: #9900ff; text-decoration-line: none;" target="_blank">www.museslabs.com</a>.</span></li>
</ul>
<span style="font-size: large;"><strong>Journal Reference</strong>:</span><br />
<ol>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Dale E. Bredesen. <a href="http://www.impactaging.com/papers/v6/n9/full/100690.html" style="color: #9900ff; text-decoration-line: none;" target="_blank"><strong>Reversal of cognitive decline: A novel therapeutic program</strong></a>.<em>Aging</em>, September </span><span style="font-size: x-small;">2014</span></li>
</ol>
</div>
experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-58544155186046402362019-08-04T16:45:00.000-04:002019-08-04T16:45:58.922-04:00How to calm those with dementia<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
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<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-75662646377470393112019-07-28T03:30:00.000-04:002019-07-28T03:30:00.259-04:00How to know which foods mix well with dementia medication<div class="separator" style="clear: both; text-align: center;">
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<span style="font-size: large;">C</span><span style="font-size: 18pt;">aregivers, and healthcare professionals,here is some great information</span><br />
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<span style="font-size: 18pt;"><br />Here is a great </span><span style="font-size: 13.5pt;"><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: 18pt;">dementia resource</span></a></span><span style="font-size: 18pt;"> for caregivers and healthcare professionals,</span><span style="font-size: 13.5pt;"><o:p></o:p></span></div>
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<i><span style="font-size: 18pt;"><br /><em>Your residents will love the <a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325">Amazon Kindle Fire</a></em></span></i><span style="font-size: 13.5pt;"><o:p></o:p></span></div>
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<span style="font-size: 18pt;"><br />Here is information on being the best </span><span style="font-size: 13.5pt;"><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: 18pt;">caregiver</span></a></span><span style="font-size: 18pt;"> you can be</span><span style="font-size: 13.5pt;"><o:p></o:p></span></div>
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<em><b><span style="font-size: 18pt;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></b></em><span style="font-size: 13.5pt;"><a href="http://easyceu.com/idevaffiliate/pages/50.php"><em><b><span style="font-family: "'times new roman'"; font-size: 18pt;">easyceu</span></b></em></a></span><strong><i><span style="font-family: "'times new roman'"; font-size: 18pt;"> or two</span></i></strong><span style="font-size: 13.5pt;"><o:p></o:p></span></div>
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<b><i><span style="font-size: 18pt;"><br /><em>Follow </em></span></i></b><strong><span style="font-size: 13.5pt;"><a href="http://twitter.com/alzheimers1"><em><span style="font-size: 18pt;">alzheimersideas</span></em></a></span></strong><em><b><span style="font-size: 18pt;"> on twitter</span></b></em><span style="font-size: 13.5pt;"><o:p></o:p></span></div>
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<h1 style="font-family: "times new roman";">
<span style="font-size: 18pt;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope [Kindle Edition</a></span></h1>
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<span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14.85px;">What's tasty and what's not for people with Alzheimer's? Find out from Teepa Snow. Learn what to expect when medication is mixed with food. Turn meals into a real time for connecting.</span><br />
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experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-12176300114507413562019-07-23T03:30:00.000-04:002019-07-23T03:30:02.640-04:00How to lower dementia risk with hearing loss treatment<span style="font-size: large;"><span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span><br /><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em><br /><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
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/></span><br />
<span style="font-size: large;"><b style="background-color: white; color: #222222; font-family: arial, sans-serif;"><span style="color: #003366; font-family: Arial, sans-serif;"><a data-saferedirecturl="https://www.google.com/url?hl=en&q=http://hear.com&source=gmail&ust=1486673486009000&usg=AFQjCNHNAuBd_WcQ-QkM77KdB_fcxczDDA" href="http://hear.com/" style="color: #1155cc; text-decoration-line: none;" target="_blank">hear.com</a><span class="Apple-converted-space"> </span>— simply good hearing</span></b></span><br />
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<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">PREVENTION & THERAPY INFOMERCIAL:</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Research shows that for every 10 decibels of hearing loss, the risk of developing dementia increases. Learn how the right hearing aids can lower your risk.</span><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"></a></span><br />
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<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Hearing Loss & Dementia</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Researchers from John Hopkins recently completed an 18-year study showing participants who experienced hearing loss had an increased risk of developing dementia. A person’s risk of developing dementia increased with the severity of hearing loss. In another study, Gallacher et al concluded that for every 10 decibels of hearing loss, the risk of developing dementia increased. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">How does hearing loss impair the brain? When the ears stop hearing certain sounds and frequencies, the brain turns off the areas needed to process those sounds. The brain also begins to shrink. MRIs show that adults with untreated hearing loss lose about a cubic centimeter of brain tissue per year.</span></span><br />
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<span style="font-size: large;">Hearing Aids May Lower the Risk of Dementia</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Hearing aids receive sounds from your environment and only amplify the sounds your ears had stopped perceiving. This technology enables the brain to recognize and process those frequencies again. Therefore, the brain continues working in those areas! By keeping your brain engaged, brain shrinkage occurs more slowly and the risk for developing dementia may be lowered. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Hearing aids also help people maintain physical, emotional, and cognitive health by giving them the chance to participate in conversations and social activities. Surveys conducted in Europe revealed hearing aid users are less tired at the end of the day and have more restful sleeps. Hearing aids users are also less depressed. In conclusion, hearing aids provide many benefits, from keeping you happy to keeping your brain healthy. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">To learn more about hearing aids and how to start wearing them, request a </span><a href="http://www.hearing-experts-at-hear.com/hearing-aids-consultation/request/?aud_p=alzheimers-campaign&act=act0000006703act&t=text&utm_source=alw&utm_medium=coop&utm_campaign=us_hea_coop_alw_product-invisible_article_alzheimers-silk_text_act0000006703act&utm_term=coop_alw_product-invisible_alzheimers-silk_text" style="background-color: white; color: #9900ff; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; text-decoration-line: none;" target="_blank">free consultation from hear.com</a><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">. Knowledgeable experts will connect you with the top hearing specialists in your area and provide you with the most effective hearing aids available. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><a href="http://www.hearing-experts-at-hear.com/hearing-aids-consultation/request/?aud_p=alzheimers-campaign&act=act0000006703act&t=text&utm_source=alw&utm_medium=coop&utm_campaign=us_hea_coop_alw_product-invisible_article_alzheimers-silk_text_act0000006703act&utm_term=coop_alw_product-invisible_alzheimers-silk_text" style="background-color: white; color: #9900ff; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; text-decoration-line: none;" target="_blank"><b>Start your consultation now »</b></a><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"> </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /></span><br />
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<span style="font-size: large;"><b><span style="color: #003366; font-family: Arial, sans-serif;"><a data-saferedirecturl="https://www.google.com/url?hl=en&q=http://hear.com&source=gmail&ust=1486673486009000&usg=AFQjCNHNAuBd_WcQ-QkM77KdB_fcxczDDA" href="http://hear.com/" style="color: #1155cc; text-decoration-line: none;" target="_blank">hear.com</a><span class="Apple-converted-space"> </span>— simply good hearing</span></b><span style="color: #5b5c5b; font-family: Arial, sans-serif;"><br />396 Alhambra Circle, Suite S-700</span></span></div>
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<span style="color: #5b5c5b; font-family: Arial, sans-serif;"><span style="font-size: large;">Coral Gables, FL 33134</span></span></div>
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experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-2287318975367275972019-07-15T12:52:00.000-04:002019-07-15T12:52:06.544-04:00Best Alzheimer's Drugs<span style="font-size: large;"><img alt="Image result for pills pictures" height="229" src="https://image.shutterstock.com/image-photo/opioid-epidemic-painkillers-drug-abuse-260nw-1032081463.jpg" width="320" /></span><br />
<span style="font-size: large;"><br /></span>
<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><b style="font-style: italic;"><a href="http://www.stmichaelshospital.com/" style="color: #9900ff; text-decoration-line: none;">St. Michael's Hospital</a>:</b><span style="font-style: italic;"> </span></span><br />
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">See safety and effectiveness rankings for four Alzheimer's drugs. Ranked on concentration, memory, alertness and mood, learn what the researchers found. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"></a></span><br />
<hr style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" />
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">An important study, ranking the safety and effectiveness of four drugs taken to enhance concentration, memory, alertness and moods, found that donepezil was most likely to effectively improve cognition in patients with Alzheimer's dementia. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">However, patients who took donepezil were more likely to experience side effects including nausea, vomiting and diarrhea than those who received a placebo, according to the study, published online in the Journal of the American Geriatrics Society.</span></span><br />
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<span style="font-size: large;">Improving Cognition in Alzheimer's</span></h3>
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<tr style="background-attachment: initial; background-clip: initial; background-image: initial; background-origin: initial; background-position: initial; background-repeat: initial; background-size: initial; color: #004e00; font-style: italic; text-align: center;"><td colspan="2" style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Drugs for Early to Midstage</span></td></tr>
<tr><th scope="col" width="137"><span style="font-size: large;">Brand Name</span></th><th scope="col" width="138"><span style="font-size: large;">Generic Name</span></th></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Aricept®</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">donepezil</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Exelon®</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">rivastigmine</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Remynil or Razadyne®</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">galantamine</span></td></tr>
<tr style="background-attachment: initial; background-clip: initial; background-image: initial; background-origin: initial; background-position: initial; background-repeat: initial; background-size: initial; color: #004e00; font-style: italic; text-align: center;"><td colspan="2" style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Drugs for Moderate to Severe Stage</span></td></tr>
<tr><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">Namenda® or Ebixa®</span></td><td style="border: 1px solid rgb(0, 0, 0); padding: 5px;"><span style="font-size: large;">memantine</span></td></tr>
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<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">In 2015, 46 million people worldwide had Alzheimer's disease, according to the study. In 2013, 146,593 people aged 65 and older in Ontario alone used cognitive enhancers, according to a 2016 Ontario Drug Policy Research report. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">"Alzheimer's dementia is the most common form of dementia in North America, and most people who have moderate to severe Alzheimer's will be on these medications," said Dr. Andrea Tricco, a scientist in the Li Ka Shing Knowledge Institute of St. Michael's Hospital and lead author of the study. "This analysis will give both patients and clinicians a full picture of how each of these drugs will likely affect their cognition, as well as their overall health."</span></span><br />
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<span style="font-size: large;">Safety & Effectiveness</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Although there have been previous reviews of the safety and effectiveness of cognitive enhancers in treating Alzheimer's dementia, the authors said this was the first to rank their comparative safety and effectiveness. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">The study used network meta-analysis, an advanced statistical analysis technique, to systematically review existing evidence from 142 clinical trials of four common cognitive enhancers administered alone or in combination published between 1996 and 2015. The number of patients in each study ranged from 13 to 2,045, and the review evaluated a total of 33,889 patients. </span></span><br />
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<span style="font-size: large;">The researchers compared the safety and effectiveness of any combination of donepezil, rivastigmine, galantamine or memantine in treating moderate to severe Alzheimer's dementia based on the results of the clinical trials that examined a number of patient outcomes, including cognition, function behaviour, global status, mortality, serious adverse events, falls, bradycardia, headache, diarrhea, vomiting and nausea. Donepezil was likely the most effective medication for Alzheimer's dementia across all effectiveness outcomes, including cognition, behavior and overall health, according to the study.</span><h3 style="color: #004e00; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Best Course of Alzheimer's Treatment</span></h3>
<span style="font-size: large;">Donepezil was also the only cognitive enhancer that reached the minimal clinically important threshold -- meaning effects on outcomes were observed clinically, as well as statistically -- on the Alzheimer's Disease Assessment cognition scale, making it the likely first choice for those patients and clinicians considering these medications, the authors said.<br /><br />Although no significant risk of serious harm, falls or reduced heart rate was associated with any of the medications in the study, the data was limited on these specific outcomes.<br /><br />Previous research by the authors found that cognitive enhancers do not improve cognition or function in people with mild cognitive impairment, and these patients experience significantly more nausea, diarrhea, vomiting and headaches.<br /><br />The findings of the current study will help guide patients and clinicians who are making decisions about the best course of treatment for Alzheimer's dementia, said Dr. Tricco.<br /><br />"The more information we are able to gather about how each of these medications can affect a patient's cognition and health, the more likely we are to be able to improve their health outcomes," she said.<br /></span><div class="moreinfo" style="border-top: 1px solid rgb(128, 128, 128); font-style: italic;">
<span style="font-size: large;"><br /><b>REFERENCE:</b></span><ul style="line-height: 1.4; list-style: disc; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px; text-indent: 0px;"><span style="font-size: large;">Andrea C. Tricco, Huda M. Ashoor, Charlene Soobiah, Patricia Rios, Areti Angeliki Veroniki, Jemila S. Hamid, John D. Ivory, Paul A. Khan, Fatemeh Yazdi, Marco Ghassemi, Erik Blondal, Joanne M. Ho, Carmen H. Ng, Brenda Hemmelgarn, Sumit R. Majumdar, Laure Perrier and Sharon E. Straus.<span> </span><a href="http://onlinelibrary.wiley.com/doi/10.1111/jgs.15069/pdf" style="color: #9900ff; text-decoration: none;">Comparative Effectiveness and Safety of Cognitive Enhancers for Treating Alzheimer's Disease: Systematic Review and Network Metaanalysis</a>. Journal of the American Geriatrics Society, September 2017 DOI: 10.1111/jgs.15069</span></li>
</ul>
<b><span style="font-size: large;">SOURCE:</span></b><ul style="line-height: 1.4; list-style: disc; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px; text-indent: 0px;"><span style="font-size: large;"><b><a href="http://www.stmichaelshospital.com/" style="color: #9900ff; text-decoration: none;">St. Michael's Hospital</a>:</b><br />St. Michael’s Hospital provides compassionate care to all who enter its doors. The hospital also provides outstanding medical education to future health care professionals in more than 29 academic disciplines. Critical care and trauma, heart disease, neurosurgery, diabetes, cancer care, care of the homeless and global health are among the Hospital’s recognized areas of expertise. Through the Keenan Research Centre and the Li Ka Shing International Healthcare Education Centre, which make up the Li Ka Shing Knowledge Institute, research and education at St. Michael’s Hospital are recognized and make an impact around the world. Founded in 1892, the hospital is fully affiliated with the U</span><span style="font-size: x-small;">niversity of Toronto.</span></li>
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experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-42330581230322290212019-07-12T12:40:00.000-04:002019-07-12T12:40:00.513-04:00How nuts help the brain<span style="font-size: large;"><img alt="Image result for peanuts pictures" height="198" src="https://cdn.pixabay.com/photo/2018/02/28/17/28/peanuts-3188500__340.jpg" width="320" /></span><br />
<span style="font-size: large;"><br /></span>
<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><a href="http://www.unisa.edu.au/" style="background-color: white; color: #33aaff; font-family: arial, tahoma, helvetica, freesans, sans-serif; font-style: italic;">University of South Australia</a></span><br />
<span style="font-size: large;"><span style="font-size: medium;"><em><span style="font-family: "times new roman"; font-size: medium;"><strong><br /></strong></span></em></span>
<span style="font-size: medium;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">In 4,000 elders, nuts boosted cognition by 60% and delayed memory decline by 2 years. See the "Healthy Nuts" chart, detailing the benefits of 10 different nuts. Watch these videos to learn why long-term, high nut consumption is a key to better thinking in older adults. </span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;"></a></span></span><br />
<hr style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" />
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Long-term, high nut consumption could be the key to better cognitive health in older people according to new research from the University of South Australia. </span></span><br />
<span style="font-size: large;"><span style="font-size: medium;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;"><br /></span></span>
<span style="font-size: medium;"><b style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;">In a study of 4822 Chinese adults aged 55+ years</b><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">, researchers found that eating more than 10 grams of nuts a day was positively associated with better mental functioning, including improved thinking, reasoning and memory.</span></span></span><br />
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Cognition & Nut Intake</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Lead researcher, UniSA's Dr Ming Li, says the study is the first to report an association between cognition and nut intake in older Chinese adults, providing important insights into increasing mental health issues (including dementia) faced by an ageing population. </span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">"Population aging is one of the most substantial challenges of the twenty-first century. Not only are people living longer, but as they age, they require additional health support which is placing unprecedented pressure on aged-care and health services," Dr Li says.</span></span><br />
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Nuts are a Preventative Dietary Modification</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">"In China, this is a massive issue, as the population is ageing far more rapidly than almost any other country in the world. </span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">"Improved and preventative health care -- including dietary modifications -- can help address the challenges that an aging population presents.</span></span><br />
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<span style="font-size: large;">
Two Teaspoons Vs. No Teaspoons of Nuts</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">"By eating more than 10 grams (or two teaspoons) of nuts per day older people could improve their cognitive function by up to 60 per cent- compared to those not eating nuts -- effectively warding off what would normally be experienced as a natural two-year cognition decline." </span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">China has one of the fastest growing aging populations. In </span><a href="https://www.bbc.com/news/world-asia-china-46772503" style="background-color: white; color: #9900ff; font-family: arial, tahoma, helvetica, freesans, sans-serif;">2029, China's population is projected to peak at 1.44 billion</a><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">, with the ratio of young to old dramatically imbalanced by the rising ranks of the elderly. </span><b style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;"><a href="http://time.com/5523805/china-aging-population-working-age/" style="color: #9900ff; text-decoration-line: none;">By 2050, 330 million Chinese will be over age 65</a>, and <a href="https://apps.who.int/iris/bitstream/handle/10665/194271/9789241509312_eng.pdf?sequence=1" style="color: #9900ff; text-decoration-line: none;">90.4 million will be over age 80</a></b><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">, representing the world's largest population of this most elderly age group.</span></span><br />
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17% Consume Nuts Regularly</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">More broadly, the </span><a href="https://www.who.int/news-room/fact-sheets/detail/ageing-and-health" style="background-color: white; color: #9900ff; font-family: arial, tahoma, helvetica, freesans, sans-serif;">World Health Organization</a><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;"> says that by 2020, the number of people aged 60 years and older will outnumber children younger than five years old. </span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">The UniSA study analysed nine waves of </span><a href="https://www.cpc.unc.edu/projects/china" style="background-color: white; color: #9900ff; font-family: arial, tahoma, helvetica, freesans, sans-serif;">China Health Nutrition Survey</a><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;"> data collected over 22 years, finding that 17 per cent of participants were regular consumers of nuts (mostly peanuts). Dr Li says peanuts have specific anti-inflammatory and antioxidant effects which can alleviate and reduce cognitive decline.</span></span><br />
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No Cure, But Nuts Offer Improvements</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">"Nuts are known to be high in healthy fats, protein and fibre with nutritional properties that can lower cholesterol and improve cognitive health," Dr Li says. </span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">"While there is no cure for age-related cognition decline and neurogenerative disease, variations in what people eat are delivering improvements for older people." </span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">The World Health Organization estimates that </span><a href="https://www.who.int/features/factfiles/dementia/en/" style="background-color: white; color: #9900ff; font-family: arial, tahoma, helvetica, freesans, sans-serif;">globally, the number of people living with dementia is at 47 million</a><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">.</span></span><br />
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Modifying Diet Worth the Effort</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">By 2030, this is projected to rise to 75 million and by 2050, global dementia cases are estimated to almost triple. </span><a href="https://www.who.int/bulletin/volumes/95/1/15-167726/en/" style="background-color: white; color: #9900ff; font-family: arial, tahoma, helvetica, freesans, sans-serif;">China has the largest population of people with dementia.x</a><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;"> </span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">"As people age, they naturally experience changes to conceptual reasoning, memory, and processing speed. This is all part of the normal ageing process," Dr. Li says. </span><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: arial, tahoma, helvetica, freesans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">"But age is also the strongest known risk factor for cognitive disease. If we can find ways to help older people retain their cognitive health and independence for longer -- even by modifying their diet -- then this absolutely worth the effort." </span></span><br />
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<span style="font-size: large;"><img src="https://cdn.theindianspot.com/wp-content/uploads/2017/01/28091802/health-benefits-of-nuts.jpg" width="100%" /></span><br />
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<b><span style="font-size: large;">SOURCE:</span></b><br />
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<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">ARTICLE: <a href="http://www.unisa.edu.au/" style="color: #9900ff; text-decoration-line: none;">University of South Australia</a></span></li>
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VIDEOS: <a href="http://nutritionfacts.org/" style="color: #9900ff; text-decoration-line: none;">NutritionFacts.org</a>
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experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-88042237989733870362019-07-06T12:29:00.000-04:002019-07-06T12:29:00.976-04:00How do lettuce and oil protect the brain<span style="font-size: large;"><img alt="250+ ORGANICALLY Grown Arugula Roquette Rocket Seeds Heirloom Non-GMO Delicious and Healthy, Eruca Sativa, from USA" height="172" src="https://images-na.ssl-images-amazon.com/images/I/51v6ZWVg-RL.jpg" width="200" /></span><br />
<span style="font-size: large;"><br /></span>
<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>
<span style="font-size: large;"><span style="background-color: white; color: #9900ff; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic; font-weight: 700;">King's College London</span></span><br />
<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>
<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">A diet that combines unsaturated fats with nitrite-rich vegetables, such as olive oil and lettuce, can protect you from hypertension and vascular dementia. Learn which foods are helpful and why.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"></a></span><br />
<hr style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" />
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">A diet that combines unsaturated fats with nitrite-rich vegetables, such as olive oil and lettuce, can protect you from hypertension, suggests a dietary study led by King's College London. Hypertension is a major risk factor for vascular dementia.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">The findings, published in the journal </span><i style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">PNAS</i><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">, help to explain why some previous studies have shown that a Mediterranean diet can reduce blood pressure.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">The Mediterranean diet typically includes unsaturated fats found in:</span></span><br />
<ul style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; line-height: 1.4; list-style-image: initial; list-style-position: initial; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">olive oil,</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">nuts</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">avocados,</span></li>
</ul>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">along with vegetables that are rich in nitrites and nitrates like: </span></span><br />
<ul style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; line-height: 1.4; list-style-image: initial; list-style-position: initial; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">spinach,</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">celery</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">carrots.</span></li>
</ul>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">When these two food groups are combined, the reaction of unsaturated fatty acids with nitrogen compounds in the vegetables results in the formation of nitro fatty acids.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">The study, supported by the British Heart Foundation, used mice to investigate the process by which these nitro fatty acids lower blood pressure, looking at whether they inhibited an enzyme known as soluble Epoxide Hydrolase which regulates blood pressure.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Mice genetically engineered to be resistant to this inhibitory process were found to maintain their high blood pressure despite being fed the type of nitro fatty acids that normally form when a Mediterranean diet is consumed. However, nitro fatty acids were found to lower the blood pressure of normal mice following the same diets.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Thus, the study concludes that the protective effect of the Mediterranean diet, combining unsaturated fats and vegetables abundant in nitrite and nitrate, comes at least in part from the nitro fatty acids generated which inhibit soluble Epoxide Hydrolase to lower blood pressure.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Professor Philip Eaton, Professor of Cardiovascular Biochemistry at King's College London, said: </span></span><br />
<blockquote style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">
<b><span style="font-size: large;">"The findings of our study help to explain why previous research has shown that a Mediterranean diet supplemented with extra-virgin olive oil or nuts can reduce the incidence of cardiovascular problems like stroke, heart failure and heart attacks."</span></b></blockquote>
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /></span>
<div class="moreinfo" style="background-color: white; border-top: 1px solid rgb(128, 128, 128); color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic;">
<span style="font-size: large;"><br /><b>Source:</b></span><ul style="line-height: 1.4; list-style-image: initial; list-style-position: initial; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><a href="http://www.kcl.ac.uk/" rel="nofollow" style="color: #9900ff; text-decoration-line: none;" target="_blank"><b><span style="font-size: large;">King's College London</span></b></a></li>
</ul>
<hr />
<span style="font-size: large;"><b>Journal Reference</b>:</span><ol>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Rebecca L. Charles, Olena Rudyk, Oleksandra Prysyazhna, Alisa Kamynina, Jun Yang, Christophe Morisseau, Bruce D. Hammock, Bruce A. Freeman, and Philip Eaton. <b>Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase</b>. <i>PNAS</i>, May 2014 DOI: <a href="http://dx.doi.org/10.1073/pnas.1402965111" rel="nofollow" style="color: #9900ff; text-decoration-line: none;" target="_blank">10.1073/pnas.1402965111</a></span></li>
</ol>
</div>
experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-55720130749741116992019-06-29T15:54:00.000-04:002019-06-29T15:54:01.018-04:00How pharmacists can help with dementia medication<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or tw</strong></span></em></span><br />
<ul style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; line-height: 1.4; list-style-image: initial; list-style-position: initial; margin: 0px 0px 0px 210px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Aston University: <a href="http://www.aston.ac.uk/" style="color: #9900ff; text-decoration-line: none;">www.aston.ac</a></span></li>
</ul>
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<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>
<span style="font-size: large;"><img alt="Image result for pill picture" height="105" src="https://www.wellrx.com/images/pill-identifier.jpg" width="320" /></span><br />
<span style="font-size: large;"><br /></span>
<span style="clear: right; float: right; font-size: large; margin-bottom: 1em; margin-left: 1em;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">HELP FROM THE PHARMACY:</span></span><br />
<ul style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; line-height: 1.4; list-style-image: initial; list-style-position: initial; margin: 0px 0px 0px 210px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;"><br /></span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Study reveals patients </span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">need help managing drugs</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Community pharmacists could be used more to support patients and carers</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Assisting carers reduces error and anxiety</span></li>
</ul>
<hr style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" />
<span style="clear: right; float: right; font-size: large; margin-bottom: 1em; margin-left: 1em;"><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"></a><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">New research funded by Pharmacy Research UK, reveals people with dementia may struggle with managing their medication – exposing them to side-effects, medication errors and an increased risk of non-adherence to drug treatment. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Researchers at Aston University, Hull University and the UEA interviewed family carers, people with dementia, nurses, GPs and community pharmacists for the proje</span><span style="background-color: white; color: #004e00; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Help with Medication Struggles</span></span><br />
<span style="clear: right; float: right; font-size: large; margin-bottom: 1em; margin-left: 1em;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Their year-long research found that as dementia develops the person struggles to manage their own medication and increasingly relies on support from family carers. This is often their partner, who may also be taking many medicines and finding the carer role stressful, thus increasing the risk of medication error. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">The study showed that for some carers this was a real burden of responsibility and that they hid their anxieties. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Lead researcher Dr. Ian Maidment, Senior Lecturer in Clinical Pharmacy at Aston said: “Our study found incorrect dosing, forgetting to give the medication and taking medicines which should have been stopped.”</span><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Professor Chris Fox, Consultant Old Age Psychiatrist from UEA’s Norwich Medical School said: “There can be severe health impact for both the patient and carer - too often in my clinical practice I come across patients and families overburdened and unclear about their medication regimes. This can result in more visits to their GP and hospital and is a cause of avoidable NHS admissions.”</span><span style="color: #004e00; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: large;">Professor Chris Fox, Co</span><span style="color: #004e00; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 28px;">nsultant Old Age Psychiatrist from UEA’s Norwich Medical School said: “There can be severe health impact for both the patient and carer - too often in my clinical practice I come across patients and families overburdened and unclear about their medication regimes. This can result in more visits to their GP and hospital and is a cause of avoidable NHS admissions.”</span></span><br />
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">Patient-Centered Care in Dementia</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Dr. Andrea Hilton from Hull University added: </span><block style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">“There is a substantial role for community pharmacists and their teams to assist carers; many pharmacists have day-to-day contact both with carers and people with dementia. Community pharmacy is in a unique position to support and embrace patient-centred care and this is currently under-utilised. This research highlights that community pharmacists should be working more with GP practices and have full access to patients’ medical records. Furthermore, home visits should be conducted for medication reviews.” </block><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Barbara Woodward-Carlton a former carer and a member of the Alzheimer’s Society Research Network highlighted: “During the years I looked after my mother who had Alzheimer's disease I wish I had known what help I could have had from community pharmacists. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">“My mother was an extremely pleasant person who always wanted to co-operate but found it incomprehensible that she should be taking any medication at all. At one point when she was very ill, I continued the medication she had been given including 'water tablets' without realising that she was dehydrated..." </span></span><br />
<h3 style="background-color: white; color: #004e00; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; margin: 10px 0px 5px; padding-top: 5px; position: relative;">
<span style="font-size: large;">patient-Centered Care in Dementia</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Dr. Andrea Hilton from Hull University added: </span><block style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">“There is a substantial role for community pharmacists and their teams to assist carers; many pharmacists have day-to-day contact both with carers and people with dementia. Community pharmacy is in a unique position to support and embrace patient-centred care and this is currently under-utilised. This research highlights that community pharmacists should be working more with GP practices and have full access to patients’ medical records. Furthermore, home visits should be conducted for medication reviews.” </block><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Barbara Woodward-Carlton a former carer and a member of the Alzheimer’s Society Research Network highlighted: “During the years I looked after my mother who had Alzheimer's disease I wish I had known what help I could have had from community pharmacists. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">“My mother was an extremely pleasant person who always wanted to co-operate but found it incomprehensible that she should be taking any medication at all. At one point when she was very ill, I continued the medication she had been given including 'water tablets' without realising that she was dehydrated..." </span></span><br />
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">"I live with the shame of not knowing that as she was barely drinking and eating I should have stopped that medication. I welcome that community pharmacists are increasingly seen as those who can advise, educate and help those of us who care for others." </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Dr. Clare Walton, Research Manager at Alzheimer’s Society said: “Seven in 10 people with dementia are also living with other health conditions and managing multiple medications which can be a tremendous challenge. Finding new and innovative ways to support people with dementia and their carers to safely and correctly age their medication is a focus for future research.” </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Dr. Maidment added: “People with dementia are amongst the most vulnerable members of society and need more support with medication management. We need to develop new ways of supporting people with dementia manage their management and then test how well these new ways work.” </span></span><br />
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<span style="font-size: large;"><br /><b>Reference Article:</b> <a href="http://onlinelibrary.wiley.com/doi/10.1111/hex.12534/full" rel="nofollow" style="color: #9900ff; text-decoration-line: none;" target="_blank">A qualitative study exploring medication management in people with dementia living in the community and the potential role of the community pharmacist</a>, Ian D. Maidment PhD, Lydia Aston MA, Tiago Moutela MA, Chris G. Fox MBBS Bsc Mmmedsci MRCPsych MD, Andrea Hilton PhD, <em>Health Expectations</em>>, doi: 10.1111/hex.12534, published 19 January 2017.<br /><br /><b>About the study</b> </span><br />
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<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">A qualitative study exploring medication management in people with dementia living in the community and the potential role of the community pharmacist is published in the journal Health Expectations.</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">The research was funded by Pharmacy Research UK (PRUK), the principal funder of pharmacy research in the UK. Founded as a result of a merger in 2012 of two previous research funding charities, PRUK has a broad programme of research in place. PRUK funds both research projects and individual bursaries to improve skills across the pharmacy sector. More information is on their website www.pharmacyresearchuk.org</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">The National Institute for Health Research (NIHR) Dementias Writing Group support was critical to develop this research. The NIHR Dementias Writing Groups are a central component of the framework for co-ordinating and supporting dementia research in the UK. The groups provide a route through which new ideas for clinical studies are developed.</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Anyone interested in registering their interest in participating in other dementia research studies can sign up to Join Dementia Research online at www.joindementiaresearch.nihr.ac.uk</span></li>
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<span style="font-size: large;"><b>About Aston University</b> </span><br />
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<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Founded in 1895 and a University since 1966, Aston University has been always been a force for change. For 50 years the University has been transforming lives through pioneering research, innovative teaching and graduate employability success. Aston is renowned for its opportunity enabler through broad access and inspiring academics, providing education that is applied and has real impact on all areas of society, business and industry. True to Aston’s Coat of Arms which bears the word ‘Forward’, in 2016 Aston held a year-long anniversary celebration to recognise its heritage and achievements, but with a focus to drive forward the next stage in the University’s exciting journey. www.aston.ac.uk/50</span></li>
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Aston's Vice Chancellor and Chief Executive, Professor Alec Cameron, is the principal academic and executive officer of the University. Alec has overall responsibility for Aston's executive management and day-to-day direction.</span></li>
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<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Aston University: <a href="http://www.aston.ac.uk/" style="color: #9900ff; text-decoration-line: none;">www.aston.ac</a></span></li>
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<span style="clear: right; float: right; font-size: large; margin-bottom: 1em; margin-left: 1em;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14.85px;"> </span></span><span style="clear: right; float: right; font-size: large; margin-bottom: 1em; margin-left: 1em;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14.85px;"><br /></span></span><span style="clear: right; float: right; font-size: large; margin-bottom: 1em; margin-left: 1em;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14.85px;"><br /></span></span><span style="clear: right; float: right; font-size: large; margin-bottom: 1em; margin-left: 1em;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif; font-size: 14.85px;"><br /></span></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-85668397165208253492019-06-27T03:30:00.000-04:002019-06-27T03:30:06.048-04:00How to bath those with dementia without a struggle<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get </span></em></strong></span><br />
<strong><em><span style="font-size: large;">an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em><br />
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<span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic;"><span style="font-size: large;">Pines Education Institute</span></span><br />
<img alt="Senior man in bath washing himself smiling : Stock Photo" src="https://media.gettyimages.com/photos/senior-man-in-bath-washing-himself-smiling-picture-id513482572?s=2048x2048" /><br />
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<span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; text-align: start;">Teepa Snow, a nationally acclaimed Alzheimer's and dementia care specialist, teaches her students how a person with dementia perceives his/her world and how to properly adapt one's own behavior to increase communication and mutual understanding. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; text-align: start;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; text-align: start;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; text-align: start;">Learn Teepa Snow's effective hands-on techniques to ease your daily caregiving tasks and increase the quality of life for your loved one or patient. In this training DVD, Teepa demonstrates effective approaches to bathing, eating, dressing, transfers, and how to respond to certain types of behaviors in patients with dementia. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; text-align: start;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; text-align: start;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; text-align: start;">"</span><b style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; text-align: start;"><a href="http://astore.amazon.com/alzheimerswee-20/detail/B005AJHHQ6" style="color: #9900ff; text-decoration-line: none;">The Art of Caregiving</a></b><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; text-align: start;">" is presented by The Pines Education Institute of SW Florida and facilitated by Teepa Snow, MS, OTR/L, FAOTA. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px; text-align: start;" /></div>
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<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;">Pines Education Institute of S.W. Florida and Teepa Snow</li>
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<br />experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-66857322881203311592019-06-24T03:30:00.000-04:002019-06-24T03:30:02.956-04:00How B vitamins decrease brain loss<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
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<b style="font-size: small; font-style: italic;">The American Academy of Neurology</b></div>
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<span style="font-size: large;"><b style="font-style: italic;">The American Academy of Neurology</b></span><br />
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<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">ST. PAUL, Minn. – A key study shows that vitamin B12 may protect against Alzheimer’s, adding more evidence to the scientific debate about whether the vitamin is effective in reducing risk of memory loss. The research is published in </span><i style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Neurology®</i><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">, the medical journal of the American Academy of Neurology</span></span><br />
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<span style="font-size: large;">“Our findings show the need for further research on the role of vitamin B12 as a marker for identifying people who are at increased risk of Alzheimer’s disease,” said study author Babak Hooshmand, MD, MSc, with Karolinska Institutet in Stockholm, Sweden. “Low levels of vitamin B12 are surprisingly common in the elderly. However, the few studies that have investigated the usefulness of vitamin B12 supplements to reduce the risk of memory loss have had mixed results.”<br /><br />For the seven-year study, researchers took blood samples from 271 Finnish people age 65 to 79 who did not have dementia at the start of the study. During that time, 17 people developed Alzheimer’s disease. Blood samples were tested for levels for homocysteine, an amino acid associated with vitamin B12, and for levels of the active portion of the vitamin, called holotranscobalamin. Too much homocysteine in the blood has been linked to negative effects on the brain, such as stroke. However, higher levels of vitamin B12 can lower homocysteine.<br /><br />The study found that for each micromolar increase in the concentration of homocysteine, the risk of Alzheimer’s disease increased by 16 percent, whereas each picomolar increase in concentration of the active form of vitamin B12 reduced risk by two percent. The results stayed the same after taking into account other factors, such as age, gender, education, smoking status, blood pressure and body mass index. The addition of folate did not appear to raise or lower the risk of Alzheimer’s disease.<br /></span><div class="separator" style="clear: both; text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjyiBxWoihuJqE7IyVLhwPboXveGpWUlQpf4-g2Afgb3wia-2Kk6u3gak9Gx9kenlC3MuovcPVh1wBv5ipKNTnR6TtSaNasyl4V81Fk91UoL0snSnOpDJIYC6WmO6Hr16dcghRyjWpOGAVM/s1600/170918-poultry.png" imageanchor="1" style="clear: right; color: #9900ff; float: right; margin-bottom: 1em; margin-left: 1em; text-decoration: none;"><span style="font-size: large;"><img border="0" data-original-height="640" data-original-width="1280" height="100" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjyiBxWoihuJqE7IyVLhwPboXveGpWUlQpf4-g2Afgb3wia-2Kk6u3gak9Gx9kenlC3MuovcPVh1wBv5ipKNTnR6TtSaNasyl4V81Fk91UoL0snSnOpDJIYC6WmO6Hr16dcghRyjWpOGAVM/s200/170918-poultry.png" style="border: none; position: relative;" width="200" /></span></a></div>
<span style="font-size: large;">“More research is needed to confirm these findings before vitamin B12 should be used solely as a supplement to help protect memory,” said Hooshmand.<br /><br />Vitamin B12 can be found in fish, poultry and other meat products.<br /></span><div class="moreinfo" style="border-top: 1px solid rgb(128, 128, 128); font-style: italic;">
<span style="font-size: large;"><br /><b>MORE INFORMATION:</b></span><ul style="line-height: 1.4; list-style: disc; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px; text-indent: 0px;"><span style="font-size: large;">The study was supported by the Karolinska Institutet, the Swedish Research Council for Medical Research, the European Commission Seventh Framework Programme, the Academy of Finland, the Ragnhild and Einar Lundströms Minne Lindhés Foundation, the Stohnes Foundation, the Gamla Tjanarinnor Foundation and the Dementia Foundation of Sweden.</span></li>
</ul>
<b><span style="font-size: large;">SOURCE:</span></b><ul style="line-height: 1.4; list-style: disc; margin: 0.5em 0px; padding: 0px 2.5em;">
<li style="border: none; margin: 0px 0px 0.25em; padding: 0px; text-indent: 0px;"><span style="font-size: large;"><b>The American Academy of Neurology</b>, an association of more than 22,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as epilepsy, dystonia, migraine, Huntington’s disease, and dementia. For </span><span style="font-size: x-small;">more information about the American Academy of Neurology, visit http://www.aan.com.</span></li>
</ul>
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<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;">. </span></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-84356152132009369602019-06-20T02:30:00.000-04:002019-06-20T02:30:00.536-04:00Easy ways to fight dementia<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><span style="font-size: medium;"><em><span style="font-family: "times new roman"; font-size: medium;"><strong><br /></strong></span></em></span>
<span style="font-size: medium;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Numerous studies show you CAN reduce risk of Alzheimer's. Learn 4 ways to improve your brain and maintain long-term health. </span></span></span><br />
<span style="font-size: large;"><span style="font-size: medium;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;"><br /></span></span>
<span style="font-size: medium;"><span style="background-color: white; color: #333333; font-family: "arial" , "tahoma" , "helvetica" , "freesans" , sans-serif;">Alzheimer's healthy lifestyle</span></span></span><br />
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<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-1424219425363324472019-06-17T03:30:00.000-04:002019-06-17T03:30:02.153-04:00How to unlock your brain' s potential<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
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<tr><td style="color: black; font-family: Arial, Helvetica, sans-serif; line-height: 18px; margin: 0px; padding-bottom: 10px;" valign="top"><span style="font-size: large;"><a data-saferedirecturl="https://www.google.com/url?q=http://click.news.uhcmedicaresolutions.com/?qs%3D2f11eb906c3c006ed42d03cda57cc629166aeb2881d9e5937ad4e38eff22b83938c388590e2229d2ee19b61d3b8d75e6fe0d1e51e8a287aea7d3ec6738be902f&source=gmail&ust=1560797552685000&usg=AFQjCNHPx-PVF_6I5mEz6SVFeQNZuVvKuQ" href="http://click.news.uhcmedicaresolutions.com/?qs=2f11eb906c3c006ed42d03cda57cc629166aeb2881d9e5937ad4e38eff22b83938c388590e2229d2ee19b61d3b8d75e6fe0d1e51e8a287aea7d3ec6738be902f" style="color: #003da1; font-weight: bold; text-decoration-line: none;" target="_blank">How are you caring for your brain?</a><br />According to the Alzheimer's Association, every 65 seconds <br />someone in the United States develops Alzheimer's disease. <br />What can you do if you want to help protect your cognitive health (the ability to think clearly, learn and remember)? More <br />research is needed, but evidence is strong that healthy <br />lifestyle habits, strong social connections and regular intellectual activity may help keep your brain active.<br /><br />June is Alzheimer's & Brain Awareness Month</span></td></tr>
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<span style="font-size: large;">Here's what to do</span></div>
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<span style="font-size: large;">1 Eat right</span></div>
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<span style="font-size: large;">2 Exercise your brain</span></div>
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<span style="font-size: large;">3 Exercise your body</span></div>
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<span style="font-size: large;">4 Socialize</span></div>
experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-31122089327194703312019-06-12T09:30:00.000-04:002019-06-12T09:30:08.104-04:00Best way to communicate with those who have dementia<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>
<span style="font-size: large;"><i style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Pines Education Institute of SW Florida and facilitated by Teepa Snow, MS, OTR/L, FAOTA. </i></span><br />
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<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Understand how people with dementia see the world. Learn the right thing to say & how to say it. See how to adapt to the world of dementia, better communicate with a person with Alzheimer's & improve their quality of life. </span></span><br />
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"><br /></span></span>
<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">This video is an excerpt of "It's All In Your Approach", a 2 1/2 hour training DVD for caregivers. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Teepa Snow, a nationally acclaimed Alzheimer's and dementia care specialist, teaches her students how a person with dementia perceives his/her world and how to properly adapt one's own behavior to increase communication and the patient's quality of life. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /></span><br />
<hr style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" />
<span style="font-size: large;"><i style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">"It's All In Your Approach" is presented by The Pines Education Institute of SW Florida and facilitated by Teepa Snow, MS, OTR/L, FAOTA.<br />© 2012, Pines Education Institute of S.W. Florida and Teepa Snow</i></span><br />
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 14.85px;"><br /></span></span>experienced healthcare professionalhttp://www.blogger.com/profile/08266183415200117714noreply@blogger.com0tag:blogger.com,1999:blog-3965671726830128098.post-21147428387874679422019-06-10T12:56:00.000-04:002019-06-10T12:56:00.534-04:00Alzheimer,s agitation-How to reduce it<span style="font-size: large;">Caregivers, and healthcare professionals,here is some great information</span><br />
<span style="font-size: large;"><br /></span><span style="font-size: large;"><span style="font-size: large;"><span style="font-size: large;">Here is a great </span><a href="http://www.amazon.com/dp/1424321840?tag=alzhesideas-20&camp=15309&creative=331441&linkCode=st1&creativeASIN=1424321840&adid=16B6P3AFFRJ0SHHXCXWR"><span style="font-size: large;">dementia resource</span></a><span style="font-size: large;"> for caregivers and healthcare professionals,</span></span></span><br />
<span style="font-size: large;"><strong><strong><em><br /></em></strong></strong><strong><strong><em><span style="font-size: large;">Follow </span></em><a href="http://twitter.com/alzheimers1"><em><span style="font-size: large;">alzheimersideas</span></em></a><em><span style="font-size: large;"> on twitter</span></em></strong></strong></span><br />
<span style="font-size: large;"><span id="btAsinTitle"><span style="font-size: large;"><a href="http://www.amazon.com/Dementia-Caregivers-Little-Book-ebook/dp/B005EYTTX6/ref=sr_1_1?ie=UTF8&qid=1318365489&sr=8-1">The Dementia Caregiver's Little Book of Hope <span style="text-transform: capitalize;">[Kindle Edition]</span></a></span></span></span><br />
<span style="font-size: large;"><span style="font-size: large;"><br /></span><em><span style="font-size: large;">Your residents will love the </span><a href="http://www.amazon.com/gp/product/B0051VVOB2/?ie=UTF8&tag=alzhesideas-20&linkCode=ur2&camp=1789&creative=9325"><span style="font-size: large;">Amazon Kindle Fire</span></a></em><br /><span style="font-size: large;"><br /></span><span style="font-size: large;">Here is information on being the best </span><a href="http://www.aquiretraining.com/idevaffiliate/idevaffiliate.php?id=103_5_1_6"><span style="font-size: large;">caregiver</span></a><span style="font-size: large;"> you can be</span><br /><strong><em><br /></em></strong><strong><em><span style="font-size: large;">Here is a way for nurses administrators, social workers and other health care professionals to get an </span></em></strong><a href="http://easyceu.com/idevaffiliate/pages/50.php"><span style="font-family: "times new roman"; font-size: large;"><strong><em>easyceu</em></strong></span></a><em><span style="font-family: "times new roman"; font-size: large;"><strong> or two</strong></span></em></span><br />
<span style="font-size: large;"><sup style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic;">1</sup><a href="http://jama.jamanetwork.com/journal.aspx" rel="nofollow" style="background-color: white; color: #9900ff; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic; text-decoration-line: none;" target="_blank"><b>The JAMA Network Journals</b></a><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic;">,</span></span><br />
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<span style="font-size: large;"><img src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEip3XFpOV_oz50dIwmFVJZPdXvyr7X7r-hsLJmghynazWGN_dAtrxmx813Dtw1uAb9ubQYNLpQ2wfVKP337P0DwkA1UPas0UMGV4jyZ-l4MNFn0DOdQcZ7PH9IIpvS5HWtHY9Q4UOjcIn0p/s200/150926-drug2.png" /></span><br />
<span style="font-size: large;"><em><span style="font-family: "times new roman"; font-size: large;"><strong><br /></strong></span></em></span>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">MEDICATION & MOOD: </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Aggression and agitation are hard challenges in dementia. An important study may offer some simple answers. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><a href="https://www.blogger.com/null" name="more" style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;"></a></span><br />
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<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">In a preliminary 10-week randomized trial, patients with probable Alzheimer disease who received the combination medication dextromethorphan-quinidine demonstrated less occurrences and severity of agitation, compared to patients who received placebo, according to a study in </span><i style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">JAMA (The Journal of the American Medical Association)</i><sup style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">1</sup><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Dr. Jeffrey Cummings, director of the Cleveland Clinic Lou Ruvo Center for Brain Health, said, "Agitation in Alzheimer's disease is one of the most disabling aspects of the disease. It interferes with the patient's life. It interferes with the ability of the caregiver to take care of the patient. It degrades the quality of life of both the patient and the caregiver." </span></span><br />
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<span style="font-size: large;">Agitation & Aggression</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Agitation and aggression are highly prevalent in patients with dementia and are associated with distress for patients and caregivers, greater risk of institutionalization, and accelerated progression to severe dementia and death. Nonpharmacological interventions are recommended as first-line therapy, but many patients fail to respond. Although many classes of psychotropic drugs are prescribed for agitation, safety concerns and modest or unproven efficacy limit their use, according to background information in the article. </span></span><br />
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<span style="font-size: large;">Drug Combo</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Dextromethorphan is commonly used in cough medicine. Quinidine is normally used to regulate an abnormal heart beat. Cummings said the combination pill had a substantial effect, greatly reducing agitation compared to the patients who got the placebo. Furthermore, he said, the caregivers also benefited. "There was a reduction in the stress experienced for caregivers of the patients who were treated with the dextromethorphan-quinidine combination. </span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">The combination of the drugs is also approved for the treatment of pseudobulbar affect (a neurologic disorder characterized by episodes of emotional displays such as crying), and there is evidence suggesting the potential benefit of these drugs for agitation. The researchers randomly assigned 220 patients to receive dextromethorphan-quinidine or placebo in stage 1. In stage 2, patients receiving dextromethorphan-quinidine continued; those receiving placebo were stratified by response and re-randomized to dextromethorphan-quinidine or placebo. The 10 week trial was conducted at 42 study sites. </span></span><br />
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<span style="font-size: large;">Trial Results</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">A total of 194 patients (88 percent) completed the study. Analysis combining stages 1 (all patients) and 2 (re-randomized placebo nonresponders) showed significantly reduced measures of agitation (occurrence and severity of symptoms). Patients treated with only dextromethorphan-quinidine had an average 51 percent reduction in the measure of agitation from baseline to week 10, compared with 26 percent for those treated with only placebo.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Adverse events included falls (8.6 percent for dextromethorphan-quinidine vs 3.9 percent for placebo), diarrhea (5.9 percent vs 3.1 percent, respectively), and urinary tract infection (5.3 percent vs 3.9 percent, respectively). Serious adverse events occurred in 7.9 percent with dextromethorphan-quinidine vs 4.7 percent with placebo. Dextromethorphan-quinidine was not associated with cognitive impairment or sedation.</span></span><br />
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<span style="font-size: large;">Conclusions</span></h3>
<span style="font-size: large;"><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">"These preliminary findings require confirmation in additional clinical trials with longer treatment duration," the authors write.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">Pending further evidence, there is a reasonably strong case to prioritize dextromethorphan-quinidine as an off-label treatment for agitation, possibly as a safer alternative to atypical antipsychotics, writes Anne Corbett, Ph.D., of King's College London, and colleagues in an accompanying editorial.</span><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;" /><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif;">"However, while further studies are conducted to verify the efficacy and safety of this approach, it will be important to achieve a robust international expert consensus regarding the prioritization of potential treatments for agitation in patients with dementia to improve the consistency of clinical practice. This approach also must understand and incorporate patient and caregiver views regarding the evaluation of risk and benefits in relation to these treatments."</span></span><br />
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<span style="font-size: large;"><b style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic;">Source:</b></span><br />
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<li style="border: none; margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;"><sup>1</sup><a href="http://jama.jamanetwork.com/journal.aspx" rel="nofollow" style="color: #9900ff; text-decoration-line: none;" target="_blank"><b>The JAMA Network Journals</b></a>, <i>Sep 22/29,2015</i></span></li>
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<span style="font-size: large;"><br style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic;" /><b style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic;">References</b><span style="background-color: white; color: #333333; font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-style: italic;">:</span></span><br />
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<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Clive Ballard, Samantha Sharp, Anne Corbett. <b>Dextromethorphan and Quinidine for Treating Agitation in Patients With Alzheimer Disease Dementia</b>. <i>JAMA</i>, 2015; 314 (12): 1233 DOI: <a href="http://dx.doi.org/10.1001/jama.2015.10215" rel="nofollow" style="color: #9900ff; text-decoration-line: none;" target="_blank">10.1001/jama.2015.10215</a></span></li>
<li style="margin: 0px 0px 0.25em; padding: 0px;"><span style="font-size: large;">Jeffrey L. Cummings, Constantine G. Lyketsos, Elaine R. Peskind, Anton P. Porsteinsson, Jacobo E. Mintzer, Douglas W. Scharre, Jose E. De La Gandara, Marc Agronin, Charles S. Davis, Uyen Nguyen, Paul Shin, Pierre N. Tariot, João Siffert. <b>Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia</b>. <i>JAMA</i>, 2015; 314 (12): 1242 DOI: <a href="http://dx.doi.org/10.1001/jama.2015.10214" rel="nofollow" style="color: #9900ff; text-decoration-line: none;" target="_blank">10.1001/jama.2015.10214</a></span></li>
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