Tuesday, November 16, 2010

How to Get Those with Advanced Dementia to Eat

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Allvoices

According to new visual perception research from a team at Boston University, using brightly colored tableware helps those with severe dementia to eat better because they have diminished sensitivity to visual contrast.. With bright "frames" for the food and beverage in front of them, those in the study increase d their food and beverage intake by 25 percent or more.

Appearing in a recent issue of the journal Clinical Nutrition, the study's findings could lead to great improvements in the nutritional welfare of individuals with advanced dementia.

The team, led by Tracy Dunne, a former postdoctoral fellow at BU's Gerontology Center and at the Geriatric Research, Education, and Clinical Center (GRECC) of the Edith Nourse Rogers Memorial Veterans Affairs (VA) Medical Center in Bedford, Mass., included Alice Cronin-Golomb, a professor in BU's Department of Psychology; Sandra Neargarder, an assistant professor of psychology at Bridgewater (Mass.) State College and BU research assistant; and, Patsy Cipolloni, an assistant research professor of anatomy and neurobiology at Boston University Medical Center.

Although 40 percent of individuals with severe dementia show a health-damaging degree of weight loss, reasons for this drop in weight have not
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How to Get Those with Advanced Dementia to Eat

Sunday, November 14, 2010

$2.6 Million To Develop Alzheimer's Treatment Using Umbilical Cord Blood Cells

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The National Institutes of Health has awarded a three-year, $2.6-million grant to the University of South Florida and Tampa-based biotechnology company Saneron-CCEL Therapeutics, Inc., to establish dosing and safety guidelines for transplanting human umbilical cord blood cells (HUBC) into animal models of Alzheimer's disease. The researchers hope to use the pre-clinical data to gain U.S. Food and Drug Administration approval to carry out clinical trials with patients suffering from Alzheimer's disease.

"Our immediate goal is to move our beneficial findings with cord blood cells into clinical trials for patients with mild to moderate Alzheimer's disease," said the grant's principal investigator Dr. Jun Tan, a USF neuroscientist and professor of psychiatry.

The NIH Phase II Small Business Technology Transfer grant is based on the success of an ongoing research partnership between USF and Saneron aimed at determining the therapeutic benefits HUBCs offer when transplanted into animal models of a variety of neurological diseases, including Parkinson's disease, Lou Gehrig's disease (ALS), Alzheimer's disease and stroke.

"Our next stage of research is

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Friday, November 12, 2010

Algal DHA Improved Memory and Learning in Healthy Adults Age 55 and Older

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The Memory Improvement with Docosahexaenoic acid (DHA) Study (MIDAS) published online in March 2010 and in the November print issue of Alzheimer's & Dementia: The Journal of the Alzheimer's Association showed that algal DHA improved memory function in healthy aging adults, by giving them memory skills of someone three years younger..
MIDAS is the first large, randomized and placebo-controlled study demonstrating the benefits of algal DHA in maintaining and improving brain health in older adults. The goal of MIDAS was to evaluate the effects of algal DHA on cognitive outcomes in healthy elderly people with a mild memory complaint. The study was funded by Martek Biosciences.
MIDAS found that healthy people over age 55 with memory complaints who took 900 mg algal DHA capsules for six months had almost double the reduction in errors on a test that measures learning and memory performance versus those who took a placebo,. The DHA was tolerated well and the people taking the DHA also had a lower heart rate, providing a benefit to their heart.
Another study, published in the latest issue of the Journal of the American Medical Association (JAMA), conducted by the Alzheimer's Disease Cooperative Study (ADCS) group, found that treatment with DHA did not show statistically significant benefit in cognitive function over placebo in a population that already had an Alzheimer's disease diagnosis and was also receiving concomitant prescription therapy. However, the study authors noted that intervention with DHA might have been effective if initiated earlier in the course of the disease in patients who do not have overt dementia. An editorial published in JAMA accompanying the study noted the same, stating that effective treatment strategies to prevent progression of Alzheimer's disease will likely need to be initiated earlier and that the treatment of mild to mo derate AD may be "too late."
Of great interest, the ADCS study demonstrated a significantly

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Wednesday, November 10, 2010

Strategies to support dementia veterans this Veteran's Day

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PRLog

Dementia,including Alzheimer disease, affects about 1 in 13 seniors,many of them veterans. As you remember our war heroes on Veteran's Day,think about what you can do for them.They did so much for us



PRLog (Press Release) – Nov 03, 2008 – Veterans who suffer from various forms of dementia, including Alzheimer disease, often have very specific care needs. It is important that these veterans are cared for by people who understand their condition and have the appropriate instruction and skills.

Therefore encourage family members of veterans to gain the training they need to care for their loved one with dementia.

All people, including those with memory loss, need human contact. They need to be hugged. They need to hear your voice. They may not know you but as long as you know who they are, that's all that matters.

Talk to them about their service to our country. Often they will share stories with you because their time in the service made a huge impression on them

Tell them how........read all of support dementia veterans this Veteran's Day

For those in nursing homes and other institutions, make sure veterans with dementia are visited often.

Monday, November 8, 2010

Is Omega 3 Effective in Treating Alzheimer's Disease?

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Digital Journal

Omega-3 has been promoted as a brain boosting drug for memory even for people with Alzheimer's disease and dementia. The latest government funded study shows different results.


However, as reported in the Washington Post,

Omega 3 did not slow mental and physical decline in older patients with Alzheimer's disease. This was a huge disappointment in a multimillion-dollar government-funded study.

"We had high hopes that we'd see some 

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Saturday, November 6, 2010

Big Pharma looking for cure for Alzheimer's

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Nearly 100 drugs are in the clinical trial phase or under federal review for use in treating Alzheimer's disease or related dementias, pharmaceutical industry analysts report.

UPI.com reports American pharmaceutical companies are focusing in on 98 new drugs for dementia, mostly Alzheimer's disease, a report released Monday by the Pharmaceutical Research and Manufacturers of America, the industry's main lobbyist, BusinesWire.com reported.

PhRMA said that the medications are either in clinical trials or are being reviewed by the U.S. Food and Drug Administration, This work shows a major commitment to Alzheimer's disease, since each new drug costs, on average

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Tuesday, November 2, 2010

Is There Another Cause of Alzheimer's Disease?

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Digital Journal

Scientists doing research at the Jewish General Hospital in Montreal have uncovered one of the root causes of Alzheimer's disease.
This information has raised the hopes of having a drug to slow down or cure or the onset of Alzheimer's disease, a devastating neurodegenerative disorder; as reported in the Montreal Gazette
A neuroscientist named Andrea LeBlanc and other scientists working with her have found that an enzyme in the brain that normally plays a role in inflammation will in certain individuals start Alzheimer's disease process. The enzyme is called Caspase-6. It causes an over-production of amyloid beta plaques that clog up the brains of Alzheimer disease victims thus impairing their memories and cognitive abilities.
LeBlanc thinks that an "estrogen-type" drug might be able to stop Caspase-6. This would effectively treat Alzheimer's disease. Right now, the research is in the early stage, It will take at least 10 years to come up with a potential drug.
"If we could slow the progression of the disease for a few years, we would win a big part of the battle," Leblanc said. "What we want to do is keep people cognitively intact for as long as possible."
Until this time, neuroscientists have focused on the "amyloid theory" as the root cause of Alzheimer's disease. However, Leblanc developed another theory: what if the amyloid plaques were not


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