Wednesday, March 4, 2009

Study suggests how Alzheimer's attacks brain

Stuff.conz

US scientists proposed a new theory of how Alzheimer's disease kills brain cells they said opens new avenues of research into treatments for the fatal, brain-wasting disease.

They believe a chemical mechanism that naturally prunes away unwanted brain cells during early brain development somehow gets hijacked in Alzheimer's disease.

"The key player we're focusing on is a protein called APP," said Marc Tessier-Lavigne, executive vice president of research drug discovery at the US biotechnology company Genentech Inc , whose study appears in the journal Nature.

Tessier-Lavigne said amyloid precursor protein, or APP -- a key building block in brain plaques found in Alzheimer's disease -- is the driving force behind this process.

"We know that APP is...read the whole article

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