White Matter Changes Could Predict Dementia Risk

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Elderly people with no memory or thinking problems are more likely to later develop thinking problems if they have a growing amount of "brain rust," or small areas of brain damage, according to a study published in the July 14, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.

For the study, researchers followed 49 people age 65 and older who had no memory or thinking problems for an average of 9.5 years. The participants had at least three brain scans and annual tests of thinking skills. During the study, 24 of the participants developed persistent cognitive impairment, or memory problems that are a potential precursor to Alzheimer's disease or another type of dementia.

The study found that those who had theread more of White Matter Changes Could Predict Dementia Risk