Friday, November 26, 2010

Culprit in Alzheimer's Disease Identified

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Results of a recent study may indicate that a protein superstructure called amyloid beta what is responsible for the damage in the brain of a person with Alzheimer's disease.

Scientists doing research at the University of California have seen that amyloid beta stops an anti-oxidant protein in the brain.They have found a way to protect that protein, and maybe even others, from harmful effects of amyloid.

"Amyloid seems to cause damage to cells. We have reported in a very detailed way one potential interaction of how amyloid can cause disease, and we found a way to stop it," said Jerry Yang.

The study of the reseachers focused on catalase-an enzyme that absorbs excess oxidants. Catalase normally helps to prevent the kind of damage seen in the brains of those with Alzheimer's disease. Work done before had found catalase proteins deposited within the amyloid plaques.

Lila Habib, the first author of the report, added amyloid to cultured neural cells and looked at its effects.

"We were able to determine that......Read all of: Culprit In Alzheimer's Disease Identified

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