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Barbara (Bobbi) Kolonay RN BSN MS CCM HNB-BC
Expert in Holistic Aging & Care Management, Speaker, Author, Consultant, Entrepreneur, "Assuring Dignified Aging"
Dementia Weekly
Recent data from several research groups have provided evidence that self-experienced decline in cognitive performance in elderly people, even those with normal performance on cognitive tests, is a risk factor for future dementia and Alzheimer's disease, and may indicate an increased likelihood for the presence of preclinical Alzheimer's.
However, research on SCD is limited by lack of a common research framework, which prevents comparability across studies and hinders deeper research into the topic.
In response, Frank Jessen, Ph.D., of the University of Bonn, Germany, led an international group of Alzheimer's researchers to form the Subjective Cognitive Decline Initiative (SCD-I). The working group includes the primary authors of the recently presented diagnostic criteria as well the lead investigators of prominent biomarker initiatives (ADNI, AIBL, DESCRIPA, Dementia Competence Network) and large population-based cohort studies. The group concluded that, "The currently available data is too limited and too heterogeneous to define SCD… as a clear-cut entity and highlights the need for intensified research on this topic."
The initial goal of the SCD-I then became to develop and disseminate a research framework for SCD, with a focus on SCD during the preclinical stage of Alzheimer's.
"This framework provides guidelines on terminology and assessment of SCD in various research settings," said Jessen. "It also describes key features that increase the likelihood that SCD in an individual is related to preclinical Alzheimer's."
Jessen says the new research framework "will greatly support research on the earliest stage of Alzheimer's."
In response, Frank Jessen, Ph.D., of the University of Bonn, Germany, led an international group of Alzheimer's researchers to form the Subjective Cognitive Decline Initiative (SCD-I). The working group includes the primary authors of the recently presented diagnostic criteria as well the lead investigators of prominent biomarker initiatives (ADNI, AIBL, DESCRIPA, Dementia Competence Network) and large population-based cohort studies. The group concluded that, "The currently available data is too limited and too heterogeneous to define SCD… as a clear-cut entity and highlights the need for intensified research on this topic."
The initial goal of the SCD-I then became to develop and disseminate a research framework for SCD, with a focus on SCD during the preclinical stage of Alzheimer's.
"This framework provides guidelines on terminology and assessment of SCD in various research settings," said Jessen. "It also describes key features that increase the likelihood that SCD in an individual is related to preclinical Alzheimer's."
Jessen says the new research framework "will greatly support research on the earliest stage of Alzheimer's."
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