Showing posts with label free radical damage. Show all posts
Showing posts with label free radical damage. Show all posts

Monday, November 6, 2017

Alzheimer's and nanosillver

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Alzheimer's is characterized by the fact that there is an overproduction of free radicals in cells. That's why incredibly tiny "nanoparticles" of silver, found in dietary supplements, cosmetics and food packaging, now worry scientists. Find out about their concerns and the products you may want to avoid.




Nanoparticles of silver, found in e.g. dietary supplements, cosmetics and food packaging, are worrying scientists. A trailblazing study from the University of Southern Denmark shows that nano-silver can penetrate our cells and cause damage.

Antibacterial Benefits

Silver has an antibacterial effect and therefore the food and cosmetic industry often coat their products with silver nanoparticles. Nano-silver can be found in:
  1. Drinking bottles
  2. Cosmetics
  3. Band aids
  4. Toothbrushes
  5. Running socks
  6. Refrigerators
  7. Washing machines
  8. Food packagings.

Cellular Changes

"Silver as a metal does not pose any danger, but when you break it down to nano-sizes, the particles become small enough to penetrate a cell wall. If nano-silver enters a human cell, it can cause changes in the cell," explain Associate Professor Frank Kjeldsen and PhD Thiago Verano-Braga, Department of Biochemistry and Molecular Biology at the University of Southern Denmark.

Together with their research colleagues they have just published the results of a study of such cell damages in the journal ACS Nano.

The researchers examined human intestinal cells, as they consider these to be most likely to come into contact with nano-silver, ingested with food.

Free Radicals in Cells

"We can confirm that nano-silver leads to the formation of harmful, so called free radicals in cells. We can also see that there are changes in the form and amount of proteins. This worries us," say Frank Kjeldsen and Thiago Verano-Braga.

A large number of serious diseases are characterized by the fact that there is an overproduction of free radicals in cells. This applies to cancer and neurological diseases such as Alzheimer's and Parkinson's.

Kjeldsen and Verano-Braga emphasizes that their research is conducted on human cells in a laboratory, not based on living people. They also point out that they do not know how large a dose of nano-silver, a person must be exposed to for the emergence of cellular changes.

"We don't know how much is needed, so we cannot conclude that nano-silver can make you sick. But we can say that we must be very cautious and worried when we see an overproduction of free radicals in human cells," they say.

Dietary Supplement

Nano-silver is also sold as a dietary supplement, promising to have an antibacterial, anti-flu and cancer-inhibatory effect. The nano-silver should also help against low blood counts and bad skin. In the EU, the marketing of dietary supplements and foods with claims to have medical effects is not allowed. But the nano-silver is easy to find and buy online.

In the wake of the University of Southern Denmark-research, the Danish Veterinary and Food Administration now warns against taking dietary supplements with nano-silver.

"The recent research strongly suggests that it can be dangerous," says Søren Langkilde from the Danish Veterinary and Food Administration to the Danish Broadcasting Corporation (DR).

Friday, September 11, 2009

High Fruit And Vegetable Intake Linked To Antioxidant Status And Cognitive Performance In Healthy Subjects

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ScienceDaily — Researchers at the Institute of Biochemistry and Molecular Biology I of the Heinrich-Heine University, Düsseldorf, Germany, investigated the relationship between fruit and vegetable intake, plasma antioxidant micronutrient status and cognitive performance in healthy subjects aged 45 to 102 years. Their results, published in the August issue of the Journal of Alzheimer’s Disease, indicated higher cognitive performance in individuals with high daily intake of fruits and vegetables

Subjects with a high daily intake (about 400 g) of fruits and vegetables had higher antioxidant levels, lower indicators of free radical-induced damage against lipids as well as better cognitive performance compared to healthy subjects of any age consuming low amounts (< 100 g/day) of fruits and vegetables. Modification of nutritional habits aimed at increasing intake of fruits and vegetables, therefore, should be encouraged to lower the prevalence of cognitive impairment.

The work was performed in collaboration with the Department of Pharmacology at Temple University in Philadelphia, Pennsylvania, the Department of Geriatrics at Perugia University, Italy, and the Department of Neurology of the St. Elisabeth Hospital in Cologne, Germany.

Dr. M. Cristina Polidori, currently at the Department of Geriatrics, Marienhospital Herne, Ruhr-University of Bochum, Germany, explains: “It is known that there is a strong association between fruit and vegetable intake and the natural antioxidant defenses of the body against free radicals. It is also known that bad nutritional habits increase the risk of developing cognitive impairment with and without dementia. With this work we show a multiple link between fruit and vegetable intake, antioxidant defenses and cognitive performance, in the absence of disease and independent of age. Among other lifestyle habits, it is recommended to improve nutrition in general and fruit and vegetable intake in particular at any age, beginning as early as possible. This may increase our chances to remain free of dementia in advanced age.”

These findings are independent of........read all of the Cognitive Performance In Healthy Subjects
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