NEW YORK (Reuters Health) - Physical weakness or "frailty" among elderly people can be an early indicator of the presence of abnormal brain plaque and tangles characteristic of Alzheimer's disease, even before the onset of memory problems, a new study hints.
The degree of Alzheimer disease "pathology" in older patients with and without dementia is directly associated with their degree of physical frailty, researchers report in the August 12th issue of the medical journal Neurology.
Dr. Aron S. Buchman, from Rush University Medical Center in Chicago and colleagues examined the brains of 165 people in their 80s who had died while participating in a long-term study called the Rush Memory and Aging Project.
While the participants were alive, they were....
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