Sunday, May 24, 2009

Dimebolin Improves Clinical Course of Mild or Moderate Alzheimer's Disease: Presented at AGS

DG Guide

By Beatriz Manzor Mitrzyk

CHICAGO -- Results of a 1-year, randomised, controlled trial show that dimebolin hydrochloride can improve cognition, function, and behaviour in patients with mild or moderate Alzheimer's disease (AD).

Rachelle Doody, MD, PhD, Baylor College of Medicine, Houston, Texas, presented the findings on May 1 at the 2009 Annual Scientific Meeting of the American Geriatrics Society (AGS).

Dimebolin, an oral antihistamine used in Russia since 1983, is a small molecule that appears to inhibit brain cell death by enhancing mitochondrial function, increasing cell viability, and promoting neurite growth. Dimebolin is under investigation in the United States for the treatment for neurodegenerative disorders like AD.

In this 1-year, double-blind, placebo......read the whole article

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