Worsening Memory May Be Too Quickly Dismissed: Could Leads to Alzheimer's (part 2)

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This condition has previously been established as a risk factor for Alzheimer's disease and other forms of dementia, with 10 percent to 20 percent progressing from mild cognitive impairment to dementia each year.

"The concept of mild cognitive impairment as a predementia manifestation of Alzheimer's disease is substantiated by studies providing biologic evidence for the presence of Alzheimer's disease in patients with mild cognitive impairment," the authors write.

"However, Alzheimer's disease-related pathologic changes in the brain evolve several years before the onset of mild cognitive impairment."

Frank Jessen, M.D., University of Bonn, Germany, and colleagues in the German Study on Aging, Cognition and Dementia in Primary Care Patients Study studied 2,415 adults age 75 or older who did not have cognitive impairment at the beginning of the study.