Worsening Memory May Be Too Quickly Dismissed: Could Leads to Alzheimer's (part 3)

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Participants were asked whether they believed their memory was becoming worse and whether or not this caused worry for them (one way for researchers to gauge the severity of memory impairments). They were then followed up one and a half and three years later and tested for mild cognitive impairment and dementia.

Individuals who had memory impairment with concern at the beginning of the study were at the highest risk for conversion to any dementia, or Alzheimer's disease-related dementia, at either follow-up.

"Subjective memory impairment without worry was independently associated with increased risk for dementia," the authors write. "This risk was roughly doubled by the presence of subjective memory impairment-related worry."

In addition, having memory impairment at the beginning of the study and mild cognitive impairment at the first follow-up increased the risk for conversion to any dementia or dementia related to Alzheimer's disease at the second follow-up; these individuals had the greatest risk for developing dementia.