Friday, May 6, 2011

Could a Diabetes Drug and a Supplement Work Together to Treat Alzheimer's Disease

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Metformin is a medication used to treat diabetes. Resveratrol is a supplement that has the benefits of drinking concentrated red wine. Doctors at Dundee University say that taking both of these things together may stop
Alzheimer's disease in its tracks.

The doctors report that metformin interferes with the development of tau which are neurofibratory tangles. Neurofibratory tangles severly limit communication between brain cells in Alzheimer's disease. They also say that Resveratrol limits the formation of these neurofibratory tangles. This research could help millions of people from getting Alzheimer's disease.

Resveratrol is a type of natural phenol, and is produced naturally by several plants when they are under the attack of harmful bacteria or fungi. Resveratrol is found in the skin of red grapes. Red wine seems to contains a high level of it.

Resveratrol was added to the cells that produce abnormal proteins called amyloid-beta. The research scientists who did this found that the levels of this abnormal protein were much lower in the cells treated with resveratrol over the untreated cells. While the scientists do not think that the amounts of resveratrol found in grapes and wine could produce the results they found in their studies using larger amounts of resveratrol. These research scientists think that grapes and wine contain molecules that, like resveratrol, are strong antioxidants. The scientists feel that resveratrol can work with other drugs like metformin to fight Alzheimer's disease.

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